Bender, C.; Kramer A. (2013): Wunden heilen: Einsatz von physikalischem Niedertemperaturplasma in der Veterinärmedizin. Hundkatzepferd 1,

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1 Literaturliste Plasmamedizin Hinweis: nachfolgende Zitate verweisen auf Arbeiten, die größtenteils mit dem kinpen MED bzw. dem Vorgängermodell kinpen 09 und anderen Kaltplasma-Geräten gewonnen wurden. Bender, C.; Matthes, R.; Kindel, E.; Kramer, A.; Lademann, J.; Weltmann, K.-D.; Eisenbeis, W.; Hübner, N.-O. (2010): The Irritation Potential of Nonthermal Atmospheric Pressure Plasma in the HETCAM Plasma Processes Polym. 7(3-4), Bender C. et al. (2011): The modified HET-CAM as a model for the assessment of the inflammatory response to tissue tolerable plasma. Toxicology in Vitro 25, Bender C. et al. (2012): Intravital Fluorescence Microscopy for the Assessment of Microcirculation and Leucoyte-Endothel Interaction after application of Tissue Tolerable Plasma in the HET-CAM. In: Mikikian, M.; Rabat H.; Robert E.; Pouvesle J.M.; editors. Book of Abstracts 4th Int Conf Plasma Medicine. Orleans, 86. Bender C. et al. (2012): Tissue tolerable plasma and polihexanide: Are synergistic effects possible to promote healing of chronic wounds? In: Machala Z., Hendsel K., Akishev Y. (ed.): Plasma for Bio-Decontamination, Medicine and Food Security. Dordrecht, Netherlands: Springer; Bender, C.; Kramer A. (2013): Wunden heilen: Einsatz von physikalischem Niedertemperaturplasma in der Veterinärmedizin. Hundkatzepferd 1, Brandenburg, R.; Lange, H.; von Woedtke, Th.; Stieber, M.; Kindel, E.; Ehlbeck, J.; Weltmann, K.-D.: Antimicrobial Effects of UV and VUV Radiation of Non-Thermal Plasma Jets IEEE Trans. Plasma Sci. 37 (2009), Clinical Plasma Medicine Core Group: Emmert, S.; Isbary, G.; Kluschke, F; Lademann, J.; Metelmann, H.R.; Podmelle, F.; Daeschlein, G.; Masur, K.; von Woedtke, T.; Weltmann, K.-D. (2013): Clinical plasma medicine position and perspectives in 2012: Paper of consent, result of the workshop Clinical Concepts in Plasma Medicine, Greifswald April 28 th, 2012 Clin. Plasma Med 1(1), 3-4. Conze, D. (2009): Analytische und mikrobiologische Untersuchungen von Flüssigkeiten nach Behandlung mit Atmosphärendruckplasma Master's thesis, Ernst-Moritz-Arndt-Universität Greifswald. Daeschlein, G. et al. (2012): In Vitro Susceptibility of Important Skin and Wound Pathogens Against Low Temperature Atmospheric Pressure Plasma Jet (APPJ) and Dielectric Barrier Discharge Plasma (DBD) Plasma Process. Polym. 9, Daeschlein, G.; Scholz, S.; Ahmed, R.; Majumdar, A.; von Woedtke, Th.; Haase, H.; Niggemeier, M.; Kindel, E.; Brandenburg, R.; Weltmann, K.-D.; Jünger, M. (2012): Cold plasma is well-tolerated and does not disturb skin barrier or reduce skin moisture JDDG 10, Daeschlein, G.; Scholz, S.; Ahmed R.; von Woedtke, Th.; Haase, H.; Niggemeier, M.; Kindel, E.; Brandenburg, R.; Weltmann, K.-D.; Jünger, M. (2012): Skin decontamination by low-temperature atmospheric pressure plasma jet and dielectric barrier discharge plasma J. Hosp. Infect. 81, Daeschlein, G.; Scholz, S.; Arnold, A.; von Woedtke, T.; Kindel, E.; Niggemeier, M.; Weltmann, K.-D.; Jünger, M. (2010): In Vitro Activity of Atmospheric Pressure Plasma Jet (APPJ) Plasma Against Clinical Isolates of Demodex Folliculorum IEEE Trans. Plasma Sci. 38(10),

2 Daeschlein, G.; Scholz, S.; von Woedtke, T.; Niggemeier, M.; Kindel, E.; Brandenburg, R.; Weltmann, K.-D.; Jünger, M. (2011): In Vitro Killing of Clinical Fungal Strains by Low-Temperature Atmospheric-Pressure Plasma Jet IEEE Transactions on Plasma Science 39, Daeschlein, G.; von Woedtke, T.; Kindel, E.; Brandenburg, R.; Weltmann, K.-D.; Jünger, M. (2010): Antibacterial Activity of an Atmospheric Pressure Plasma Jet Against Relevant Wound Pathogens in vitro on a Simulated Wound Environment Plasma Processes Polym. 7(3-4), Fluhr, J. W.; Sassning, S.; Lademann, O.; Darvin, M. E.; Schanzer, S.; Kramer, A.; Richter, H.; Sterry, W.; Lademann, J. (2012): In vivo skin treatment with tissue-tolerable plasma influences skin physiology and antioxidant profile in human stratum corneum Exp Dermatol 21(2), Foest, R.; Bindemann, T.; Brandenburg, R.; Kindel, E.; Lange, H.; Stieber, M.; Weltmann, K.-D. (2007): On the Vacuum Ultraviolet Radiation of a Miniaturized Non-thermal Atmospheric Pressure Plasma Jet Plasma Processes Polym. 4(S1), Foest, R.; Fricke, K.; Kindel, E.; Lange, H.; Schäfer, J.; Stieber, M.; Weltmann, K.-D. (2009): Kalte Normaldruck-Jetplasmen zur lokalen Oberflächenbehandlung Vak. Forsch. Prax. 21(6), Foest, R.; Kindel, E.; Lange, H.; Ohl, A.; Stieber, M.; Weltmann, K. D. (2007): RF capillary jet a tool for localized surface treatment Contrib. Plasma Phys. 47(1-2), Foest, R.; Kindel, E.; Ohl, A.; Stieber, M.; Weltmann, K. (2005): Non-thermal atmospheric pressure discharges for surface modification PLASMA PHYSICS AND CONTROLLED FUSION 47(Sp. Iss. SI Suppl. 12B), Fricke, K.; Steffen, H.; von Woedtke, T.; Schröder, K.; Weltmann, K.-D. (2011): High Rate Etching of Polymers by Means of an Atmospheric Pressure Plasma Jet Plasma Processes Polym. 8(1), Fricke, K.; Tresp, H.; Bussiahn, R.; Schröder, K.; von Woedtke, T.; Weltmann, K.-D. (2012): On the Use of Atmospheric Pressure Plasma for the Bio-Decontamination of Polymers and Its Impact on Their Chemical and Morphological Surface Properties Plasma Chemistry and Plasma Processing 32(4), Funk, W.; Podmelle, F.; Guiol, C.; Metelmann, H.R.: Aesthetic satisfaction scoring Introducing an aesthetic numeric Analogue scale (ANA-scale) J Cranio-Maxillofac Surg 2012, 40(5), Haehnel, M.; von Woedtke, Th.; Weltmann, K.-D.: Influence of the Air Humidity on the Reduction of Bacillus Spores in a Defined Environment at Atmospheric Pressure Using a Dielectric Barrier Surface Discharge Plasma Process. Polym. 7(2010), Haertel, B.; Wende, K.; von Woedtke, T.; Weltmann, K. D.; Lindequist, U. (2011): Non-thermal atmospheric-pressure plasma can influence cell adhesion molecules on HaCaTkeratinocytes Experimental Dermatology 20(3), Hammann, A.; Hübner, N.-O.; Bender, C.; Ekkernkamp, A.; Hartmann, B.; Hinz, P.; Kindel, E.; Koban, I.; Koch, S.; Kohlmann, T.; Lademann, J.; Matthes, R.; Müller, G.; Titze, R.; Weltmann, K.-D.; Kramer, A. (2010): Antiseptic Efficacy and Tolerance of Tissue-Tolerable Plasma Compared with Two Wound Antiseptics on Artificially Bacterially Contaminated Eyes from Commercially Slaughtered Pigs Skin Pharmacol. Physiol. 23, Holtz, S. (2010): Erfassung plasmabedingter DNA-Schaden durch neutrale Einzelzellgelelektrophorese (Comet Assay) und Mikronukleus Test Master's thesis, Ernst-Moritz-Arndt-Universität Greifswald.

3 Hübner, N.-O.; Matthes, R.; Koban, I.; Randler, C.; Müller, G.; Bender, C.; Kindel, E.; Kocher, T.; Kramer, A. (2010): Efficacy of chlorhexidine, polihexanide and tissue-tolerable plasma against Pseudomonas aeruginosa biofilms grown on polystyrene and silicone materials Skin Pharmacol. Physiol. 23 Suppl, Isbary, G.; Heinlin, J.; Shimizu, T.; Zimmermann, J. L.; Morfill, G.; Schmidt, H.-U.; Monetti, R.; Steffes, B.; Bunk, W.; Li, Y.; Klaempfl, T.; Karrer, S.; Landthaler, M.; Stolz, W. (2012): Successful and Safe Use of 2 Min Cold Atmospheric Argon Plasma in Chronic Wounds: Results of A Randomized Controlled Trial Br J Dermatol. Isbary, G.; Morfill, G.; Schmidt, H. U.; Georgi, M.; Ramrath, K.; Heinlin, J.; Karrer, S.; Landthaler, M.; Shimizu, T.; Steffes, B.; Bunk, W.; Monetti, R.; Zimmermann, J. L.; Pompl, R.; Stolz, W. (2010): A first prospective randomized controlled trial to decrease bacterial load using cold atmospheric argon plasma on chronic wounds in patients Br J Dermatol 163(1), Kalghatgi, S.; Friedman, G.; Fridman, A.; Morss Clyne, A. (2010): Endothelial cell proliferation is enhanced by low dose non-thermal plasma through fibroblast growth factor-2 release Ann Biomed Eng. 38, Kiss G. et al. (1997): New combination for the therapy of canine otitis externa I Microbiology of otitis externa Journal of Small Animal Practice 38, Koban, I.; Hübner, N.-O.; Matthes, R.; Welk, A.; Kindel, E.; Weltmann, K.-D.; Kramer, A.; Kocher, T. (2009): Antiseptische Wirksamkeit ausgewahlter Wirkstoffe und von tissue tolerable plasma (TTP) auf C. albicans-biofilme hat der Reifegrad des Biofilms einen Einfluss? GMS Krankenhaushyg Interdiszip 4(2), Doc09. Koban, I.; Matthes, R.; Hübner, N.-O.; Welk, A.; Meisel, P.; Holtfreter, B.; Sietmann, R.; Kindel, E.; Weltmann, K.-D.; Kramer, A.; Kocher, T. (2010): Treatment of Candida albicans biofilms with low temperature plasma induced by dielectric barrier discharge and atmospheric pressure plasma jet New J. Phys. 12(7), Kramer, A.; Assadian, O.; Below, H.; Bender, C.; Hammann, A.; Hartmann, B.; Hübner, N.-O.; Kocher, T.; Lademann, J.; Matthes, R.; Koban, I.; Weltmann, K.-D. (2010): Perspektiven der Plasmamedizin Vak. Forsch. Prax. 22(2), Kramer, A.; Assadian, O.; Below, H.; Willy, C.: Wound antiseptics today an overview Willy, C. (ed): Antiseptics in surgery update Lindqvist, Berlin 2013: Kramer, A.; Bender, C.; Assadian, O.; Ekkernkamp, A.; Hartmann, B.; Heidecke, C.D.; Hinz, P.; Koban, I.; Masur, K.; Matthes, R.; Metelmann, H.R.; Partecke, L.I.; Reuter, S.; Sckell, A.; Weltmann K.-D.; Lademann, J.: Physikalisches kaltes Atmosphärendruckplasma als aussichtsreiche Option zur Behandlung chronischer Wunden Physical cold atmospheric pressure plasma as promising option for treatment of chronic wounds. Hyg Med 2013; Kramer, A.; Hübner, N.-O.; Assadian, O.; Below, H.; Bender, C.; Benkhai, H.; Broker, B.; Ekkernkamp, A.; Eisenbeis, W.; Hammann, A.; Hartmann, B.; Heidecke, C.; Hinz, P.; Koban, I.; Koch, S.; Kocher, T.; Lademann, J.; Lademann, O.; Lerch, M.; Maier, S.; Matthes, R.; Müller, G.; Partecke, I.; Randler, C.; Weltmann, K.-D.; Zygmunt, M. (2009): Chancen und Perspektiven der Plasmamedizin durch Anwendung von gewebekompatiblen Atmosphärendruckplasmen (Tissue Tolerable Plasmas, TTP) GMS Krankenhaushyg Interdiszip 4(2), Doc10. Kramer, A.; Hübner, N.-O.; Weltmann, K.-D.; Lademann, J.; Ekkernkamp, A.; Hinz, P.; Assadian, O. (2008): Polypragmasia in the therapy of infected wounds - conclusions drawn from the perspectives of low temperature plasma technology for plasma wound therapy GMS Krankenhhyg Interdiszip 3(1), Doc13.

4 Kramer, A.; Lademann, J.; Bender, C.; Sckell, A.; Hartmann, B.; Münch, S.; Hinz, P.; Ekkernkamp, A.; Matthes, R.; Koban, I.; Partecke, I.; Heidecke, C.D.; Masur, K.; Reuter, S.; Weltmann, K.D.; Koch, S.; Assadian, O.: Suitability of tissue tolerable plasmas (TTP) for the management of chronic wounds Clinical Plasma Medicine, 1(1), Lademann, J.; Richter, H.; Alborova, A.; Humme, D.; Patzelt, A.; Kramer, A.; Weltmann, K.-D.; Hartmann, B.; Ottomann, C.; Fluhr, J.; Hinz, P.; Hübner, G.; Lademann, O. (2009): Risk assessment of the application of a plasma jet in dermatology J Biomed Opt 14(5), Lademann, J.; Ulrich, C.; Patzelt, A.; Richter, H.; Kluschke, F.; Klebes, M.; Lademann, O.; Kramer, A.; Weltmann, K.; Lange-Asschenfeldt, B. (2013): Risk assessment of the application of tissue-tolerable plasma on human skin Clinical Plasma Medicine (0). Lademann, O; Kramer, A.; Richter, H.; Patzelt, A.; Meinke, M.C.; Czaika, V.; Weltmann K.-D.; Harmann, B.; Koch, S.: Skin disinfection by plasma-tissue interaction: comparison of the effectivity of tissue-tolerable plasma and a standard antiseptic Skin Pharmacol Physiol 2011; 24(5): Lademann, O.; Richter, H.; Patzelt, A.; Alborova, A.; Humme, D.; Weltmann, K.-D.; Hartmann, B.; Hinz, P.; Kramer, A.; Koch, S. (2010): Application of a plasma-jet for skin antisepsis: analysis of the thermal action of the plasma by laser scanning microscopy Laser Phys. Lett. 7(6), Landsberg, K.; Ch., S.; Darm, K.; Wende, K.; Daeschlein, G.; Kindel, E.; Weltmann, K.-D.; Von Woedtke, T. (2010): Use of Proteomics to Investigate Plasma-Cell Interactions Plasma Medicine 1(1), Laroussi M.L.: Low temperature Plasma for Medicine? IEEE Transactions on Plasma Science, Vol. 37, No. 6, June Matthes, R.; Bender, C.; Hübner, N.-O.; Müller, G.; Kohl, K.; Mentz, J.; Koban, I.; Kindel, E.; Kocher, T.; Weltmann, K.-D.; Lademann, J.; Kramer, A. (2009): Beeinflussung der Penetration von Pseudomonasaeruginosa in eine 3-D-Epidermis und Inaktivierung mitgewebevertraglichem Plasma GMS Krankenhaushyg Interdiszip 4(2), Doc08. Metelmann, H.-R.; von Woedtke, T.; Bussiahn, R.; Weltmann, K.-D.; Rieck, M.; Khalili, R.; Podmelle, F.; Waite, P. D. (2012): Experimental Recovery of CO 2-Laser Skin Lesions by Plasma Stimulation Am. J. Cos. Surg. 29. Metelmann, H.-R.; Vu, T. T.; Do, H. T.; Le, T. N. B.; Hoang, T. H. A.; Phi, T. T. T.; Luong, T. M. L.; Doan, V. T.; Nguyen, T. T. H.; Nguyen, T. H. M.; Nguyen, T. L.; Le, D. Q.; Le, T. K. X.; von Woedtke, T.; Bussiahn, R.; Weltmann, K.-D.; Khalili, R.; Podmelle, F. (2013): Scar formation of laser skin lesions after cold atmospheric pressure plasma (CAP) treatment: A clinical long term observation Clin Plasma Med 2013; 1(1): Nastuta A.V. et al. (2011): Stimulation of wound healing by helium atmospheric pressure plasma treatment. Journal of Physics D Applied Physics 44, Nosenko, T.; Shimizu, T. & Morfill, G. E. (2009): Designing plasmas for chronic wound disinfection New Journal of Physics 11(11), Pipa, A.V.; Reuter, S.; Foest, R.; Weltmann, K.-D. (2012): Controlling the NO production of an atmospheric pressure plasma jet Journal of Physics D: Applied Physics 45(8),

5 PRODUCTS, S. C. O. C. (2006): Opinion on Biological effects of ultraviolet radiation relevant to health with particular reference to sun beds forcosmetic purposes (SCCP/0949/05) Technical report, EUROPEAN COMMISSION, HEALTH & CONSUMER PROTECTION DIRECTORATE- GENERAL, Directorate C - Public Health and Risk Assessment, C7 - Risk assessment. Reuter, S.; Winter, J.; Iseni, S.; Peters, S.; Schmidt-Bleker, A.; Dünnbier, M.; Schäfer, J.; Foest, R.; Weltmann, K.-D. (2012): Detection of ozone in a MHz argon plasma bullet jet Plasma Sources Science and Technology 21(3), Schmid, K. (2008): Der Mikrowellen-Plasma-Sterilisator Ein neuer Weg zur Wundsterilisation Master's thesis, Medizinisch Technische Akademie Esslingen MT 31. Shimizu, T.; Nosenko, T.; Morfill, G. E.; Sato, T.; Schmidt, H.-U. & Urayama, T. (2010): Characterization of Low-Temperature Microwave Plasma Treatment With and Without UV Light for Disinfection Plasma Processes and Polymers 7(3-4), Shimizu, T.; Steffes, B.; Pompl, R.; Jamitzky, F.; Bunk, W.; Ramrath, K.; Georgi, M.; Stolz, W.; Schmidt, H.-U.; Urayama, T.; Fujii, S. & Morfill, G. E. (2008): Characterization of Microwave Plasma Torch for Decontamination Plasma Processes and Polymers 5(6), Vogelsang, A.; Ohl, A.; Steffen, H.; Foest, R.; Schröder, K.; Weltmann, K.-D. (2010): Locally Resolved Analysis of Polymer Surface Functionalization by an Atmospheric Pressure Argon Microplasma Jet with Air Entrainment Plasma Processes Polym. 7(1), Weltmann, K.-D.; Brandenburg, R.; von Woedtke, T.; Ehlbeck, J.; Foest, R.; Stieber, M.; Kindel, E. (2008): Antimicrobial treatment of heat sensitive products by miniaturized atmospheric pressure plasma jets (APPJs) J. Phys. D: Appl. Phys. 41(19), Weltmann, K.-D.; Kindel, E.; Brandenburg, R.; Meyer, C.; Bussiahn, R.; Wilke, C.; von Woedtke, T. (2009): Atmospheric Pressure Plasma Jet for Medical Therapy: Plasma Parameters and Risk Estimation Contrib. Plasma Phys. 49(9), Weltmann, K.-D.; Kindel, E.; von Woedtke, T.; Hahnel, M.; Stieber, M.; Brandenburg, R. (2010): Atmospheric-pressure plasma sources: Prospective tools for plasma medicine Pure Appl. Chem. 82(6), Weltmann, K.-D.; von Woedtke, T. (2011): Campus PlasmaMed From Basic Research to Clinical Proof IEEE Transactions on Plasma Science 39, Weltmann, K.-D.; von Woedtke, Th.: Basic requirements for plasma sources in medicine Eur. Phys. J. Appl. Phys. 55 (2011) Weltmann, K.-D.; Winter, J.; Polak, M.; Ehlbeck, J.; von Woedtke, Th.: Atmospheric pressure plasmas for decontamination of complex medical devices In: Machala, Z.; Hensel, K.; Akishev Y. (Eds.): Plasma for bio-decontamination, medicine and food security NATO Science for Peace and Security Series - A: Chemistry and Biology, Springer 2012, Wende, K.; Landsberg, K.; Lindequist, U.; Weltmann, K.-D.; von Woedtke, T.: (2010): Distinctive Activity of a Nonthermal Atmospheric-Pressure Plasma Jet on Eukaryotic and Prokaryotic Cells in a Cocultivation Approach of Keratinocytes and Microorganisms IEEE Trans. Plasma Sci. 38 (9), 2479.