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A: Subkortikale Läsionen 1 2 Z=+16mm Z=-1mm Z=+16mm 3 4 Z=+24mm Z=+16mm Z=-1mm Z=-12mm Z=+24mm Z=+16mm 5 6 Z=+24mm Z=+16mm Z=+16mm Z=-1mm 7 8 Z=+24mm Z=+16mm Z=-1mm Z=+24mm Z=+16mm Z=-1mm 9 10 Z=+24mm Z=-20mm 11 12 Z=-20mm Z=-20mm 16
B: Kortikal-Subkortikale Läsionen 13 Z=+60mm Z=+50mm Z=+40mm Z=+32mm Z=+24mm Z=+16mm Z=-1mm 14 Z=+60mm Z=+50mm Z=+40mm Z=+32mm Z=+24mm Z=+16mm Z=-1mm Z=-12mm 15 Z=+40mm Z=+32mm Z=+24mm Z=+16mm Z=-1mm 16 Z=+40mm Z=+32mm Z=+24mm Z=+16mm Z=-1mm 17 Z=+50mm Z=+40mm Z=+32mm Z=+24mm Z=+16mm Z=-1mm 18 Z=+50mm Z=+40mm Z=+32mm Z=+24mm Z=+16mm Z=-1mm 18
9' 19 20 Z=+40mm Z=+32mm Z=+24mm Z=+16mm Z=-1mm Z=-12mm Z=+50mm Z=+40mm Z=+32mm Z=+24mm Z=+16mm Z=-1mm Z=-12mm
C: Parietale Läsionen 21 Z=+50mm Z=+40mm Z=+32mm Z=+24mm Z=+16mm Z=-1mm 22 Z=+50mm Z=+40mm Z=+32mm Z=+24mm Z=+16mm Z=-1mm Z=-12mm 23 Z=+60mm Z=+50mm Z=+40mm Z=+32mm Z=+24mm Z=+16mm 24 Z=+60mm Z=+50mm Z=+40mm Z=+32mm Z=+24mm Z=+16mm Z=-1mm Z=-12mm 94
D: Perizentrale Läsionen 25 Z=+65mm Z=+60mm Z=+50mm Z=+40mm Z=+32mm Z=+24mm Z=+16mm 26 Z=+60mm Z=+50mm Z=+40mm Z=+32mm Z=+24mm Z=+16mm Z=-1mm 27 Z=+65mm Z=+60mm 28 Z=+60mm Z=+50mm Z=+40mm 29 Z=+60mm Z=+50mm Z=+40mm Z=+24mm Z=+16mm Z=-1mm Z=-12mm 30 Z=+65mm Z=+60mm Z=+50mm Z=+40mm Z=+16mm 9&
91 31 32 Z=+32mm Z=+24mm Z=+16mm Z=+60mm Z=+50mm Z=+40mm Z=+32mm Z=+24mm Z=+16mm Z=+60mm Z=+50mm Z=+40mm
E: Prämotorische Läsionen 33 Z=+50mm Z=+40mm Z=+32mm Z=+24mm Z=+16mm Z=-1mm Z=-12mm 34 Z=+50mm Z=+40mm Z=+32mm Z=+24mm Z=+16mm Z=-1mm Z=-12mm 35 Z=+32mm Z=+24mm Z=+16mm Z=-1mm Z=-12mm 36 Z=+60mm Z=+50mm Z=+40mm Z=+32mm Z=+24mm Z=+16mm Z=-1mm $. /13 8 $ 4 =(%A@@6 #! 9 < 8 / 46 / '( " 311 4 6 $ " H : 38" /H F'/ '!/H ' / D'1 D2(9,(.(0(@ 99
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20 Z=+40mm Z=+32mm Z=+24mm Z=+16mm Z=-1mm Z=-12mm 21 Z=+50mm Z=+40mm Z=+32mm Z=+24mm Z=+16mm Z=-1mm 22 Z=+50mm Z=+40mm Z=+32mm Z=+24mm Z=+16mm Z=-1mm Z=-12mm 26 Z=+60mm Z=+50mm Z=+40mm Z=+32mm Z=+24mm Z=+16mm Z=-1mm 33 Z=+50mm Z=+40mm Z=+32mm Z=+24mm Z=+16mm Z=-1mm Z=-12mm 35 9( Z=+32mm Z=+24mm Z=+16mm Z=-1mm Z=-12mm $0 /' 1 #! 9 < 8/46/'( " 311 4 6 D ' 1 2$.
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Patienten ohne Besserung 1 Z=+16mm Z=-1mm 4 Z=+24mm Z=+16mm 17 Z=+50mm Z=+40mm Z=+32mm Z=+24mm Z=+16mm Z=-1mm 23 Z=+60mm Z=+50mm Z=+40mm Z=+32mm Z=+24mm Z=+16mm 24 Z=+60mm Z=+50mm Z=+40mm Z=+32mm Z=+24mm Z=+16mm Z=-1mm Z=-12mm $ @ / ' : : #! 9 < 8/ 46 / '( " 311 4 6 D'1 2(%%$. 96
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/!--#> +!B : ;+ 44 ++ 4'<C 55 + 5 0 + > 55 5 0!--#> 9C2 UI 2C1! #>!-- + 1C2 UI 1C3 >>++ + )C!--1C4UI4C8+!--#>"55+2C2UI 9C9??!--#> +"55 C5 :!--2C2UI4C1C!--8C'UI2C1< 5 :!--2C6UI4C(C!--6C6UI1C'<)5 + >?+ )+#>!--9C9UI &C&!--3C2UI9C9 Punktzahl 8,0 7,0 6,0 5,0 4,0 3,0 2,0 1,0 0,0 Subkortikale 16,0 14,0 12,0 10,0 8,0 6,0 4,0 2,0 1 2 3 4 5 0,0 Kortikal- Subkortikale Punktzahl Parietale Perizentrale Prämotorische Subkortikale Kortikal- Subkortikale Parietale Perizentrale Prämotorische 1 2 3 4 5 Arm ESS Hand ESS $ %> # ; = '11$=8$ '11(8$ '9 $8 4 6 IJ8" 8"" IJ8" 4 6$ 2'
Punktzahl *22# '11 $ 1 )/G;55:;+ 44++44< +7/% :5V'C''&<C + > &3 ; + 75:5 Z'C''4< + >?? + 557+?7+!--#>29C6UI&4+ 63C& UI 44C9 %!--#> + 7 3(C6 UI 42C& 62C9 UI 41C4 C 7 5 + >:5 V'C''2<C 7 C G + ; />? >:5V'C91&< D/+C >/!--C + ; + 75.D 7 :5V'C'&9< 100,0 90,0 80,0 70,0 60,0 50,0 40,0 30,0 20,0 10,0 0,0 Lyse 1 keine2 Lyse Aufnahme ESS Verlaufs ESS $%% D : $ =8$ '11 (8$ '9IJ8"&8""$ # % D /+ :5Z'C''4C *V'C233< #/ > ;;9 ;;( + + 7:5Z'C'&C*V'C3(1<C ; D # / > 5 /+ > >/!-- :++4&<)" 24
+ 7 #/! :++4&< 100 ESS Änderung 80 60 40 20 0 0 20 40 60 80 100 Mismatch Volumen (ml) $%23&8""- '+8'.#) 4 6 8 4K6'!--% +!B :;+ 44< C $ ++75 > :5V'C'4<C:5V'C'93<.D>C+7 #>!-- + + 7 &C( UI&C2 +2C4UI4C6+7:++41< +!--#> 9C9UI2C'+7C" 6C4UI1C6+7 2&
8,0 16,0 7,0 14,0 6,0 12,0 Punktzahl 5,0 4,0 3,0 Punktzahl 10,0 8,0 6,0 2,0 4,0 1,0 2,0 0,0 1 2 Lyse keine Lyse 0,0 1 2 Lyse keine Lyse Arm ESS Hand ESS $%*: $ $ $ =8$ '11 ( 8$ '9 $8 4 6IJ8"8""IJ8"4 6$ 21
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Newton Sekunden Newton Sekunden Änderung der Kraft 20,0 20,0 15,0 15,0 10,0 10,0 5,0 5,0 0,0 1 2 3 4 5 6 7 8 9 10 0,0 1 2 3 4 5 6 7 8 9 10 Änderung der Bewegungsdauer 1,5 1,5 1,0 1,0 0,5 0,5 0,0 1 2 3 4 5 6 7 8 9 10 0,0 1 2 3 4 5 6 7 8 9 10 Änderung der Bewegungsfrequenz 5,0 5,0 4,0 4,0 3,0 3,0 Hz Hz 2,0 2,0 1,0 1,0 0,0 1 2 3 4 5 6 7 8 9 10 Tage nach Hirninfarkt 0,0 1 2 3 4 5 6 7 8 9 10 Tage nach Hirninfarkt Kontraläsionelle Hand Ipsiläsionelle Hand $ %+ L / ' M /" 46H 38" 46H'! 46H ' 46H' 46 $ =8$ ) ( 8$ L9 IJ8"! ) 9 %! 34D96( 4"6;N!4!6 :9 22
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> # + :5 V 'C'1< 5 :++42< Kraft Bewegungsdauer Bewegungsfrequenz 120,00 100,00 * 120,00 120,00 ** *** *** 100,00 100,00 80,00 80,00 80,00 Prozent 60,00 60,00 60,00 40,00 40,00 40,00 20,00 20,00 20,00 0,00 0 1 2 3 Thrombolyse keine Thrombolyse Kontrollgruppe 0,00 0 1 2 3 Thrombolyse keine Thrombolyse Kontrollgruppe 0,00 0 1 2 3 Thrombolyse keine Thrombolyse Kontrollgruppe $%, #!9 1 34J16(:941J6 :9N! 4J16! $!1 4B 1 O >(>,( BB 1? >(>>%(BBB1O>(>>%6$=8$ '11(8$ '!IJ8"?>O 5 ++ +"55+?>+7+ 1;+C+7$O :++1;< 23
Sekunden Sekunden Änderung der Kraft 8,0 8,0 7,0 7,0 6,0 6,0 5,0 5,0 4,0 4,0 Newton 3,0 Newton 3,0 2,0 2,0 1,0 1,0 0,0 1 2 3 4 5 6 7 8 0,0 1 2 3 4 5 6 7 8 Änderung der Bewegungsdauer 1,2 1,2 1,0 1,0 0,8 0,8 0,6 0,6 0,4 0,4 0,2 0,2 0,0 1 2 3 4 5 6 7 8 0,0 1 2 3 4 5 6 7 8 Änderung der Bewegungsfrequenz 3,5 3,5 3,0 3,0 2,5 2,5 Hz 2,0 Hz 2,0 1,5 1,5 1,0 1,0 0,5 0,5 0,0 1 2 3 4 5 6 7 8 0,0 1 2 3 4 5 6 7 8 Tage nach Hirninfarkt Tage nach Hirninfarkt Kontraläsionelle Hand Ipsiläsionelle Hand $%. L / ' / 1 46 ' / 146$=8$ ) ( 8$ L9 IJ8"! ) 9 %! 3 4D96( 4"6 ;N! 4!6 :9 26
Newton Sekunden Newton Sekunden ***311 % "5:++43< C>+ # 5 > A C $O # 5 Änderung der Kraft 2,0000 2,0000 1,5000 1,5000 1,0000 1,0000 0,5000 0,5000 0,0000 1 2 3 4 0,0000 1 2 3 4 Änderung der Bewegungsdauer 2,0000 2,0000 1,5000 1,5000 1,0000 1,0000 0,5000 0,5000 0,0000 1 2 3 4 0,0000 1 2 3 4 Änderung der Bewegungsfrequenz 2,0000 2,0000 1,5000 1,5000 Hz 1,0000 Hz 1,0000 0,5000 0,5000 0,0000 1 2 3 4 0,0000 1 2 3 4 Messtage Messtage Rechte Hand Linke Hand $%0) ) 31 46H 46 $ =8$ ) ( 8$ L9 IJ8"! ) 3 4D96( 4"6;N!4!6 :9 28
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