Falk Workshop. GERD: Gastroesophageal Reflux Disease. September 5, 2013 Congress Graz Graz, Austria. Program. Awarded with.

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Falk Workshop GERD: Gastroesophageal Reflux Disease September 5, 2013 Congress Graz Graz, Program Awarded with 6 CME credits

Preface... 4 Scientific Program......................... 6 List of Speakers... 8 Information... 10 6 credit hours (CME) have been awarded for the Falk Workshop by the European Union of Medical Specialists (UEMS) - European Board of Gastroenterology (EBG). 3

Preface Dear Colleagues, Fifty years ago, Henry Bockus three-volume textbook, Gastroenterology (2 nd edition, 1963), comprised 2300 pages. Of these, only 13 were devoted to esophagitis but 6 to tuberculosis of the esophagus. Today, out of 2300 pages in a comprehensive gastroenterology textbook, some 300 would be devoted to gastroesophageal reflux disease (GERD) and at the most half a page to tuberculosis. When one of us (GJK) was a GI fellow in Zurich, Switzerland, and André Blum asked him in 1972 to start working on gastroesophageal reflux disease, the first thought was that it was a rare problem and mainly of academic interest. Soon thereafter it came to be a very important disease 1, 2. Things have indeed changed: GERD and its complications such as Barrett s esophagus have become one of the most important subjects in gastroenterology, as reflected in the large number of papers devoted to it every year. GERD is probably the number one reason for today s enormous use of proton pump inhibitors. We would like to welcome you to this international workshop on GERD and to update you on the latest news about it. We would also like to thank the Falk Foundation for making this scientific event possible. Remember Graz from 2003 as the European Cultural Capital? Come and learn about GERD from a renowned international faculty in this historic city. Auenbrugger, Kepler, Escherich and Loewi, among others, have also lectured here! Andreas J. Eherer, M.D. Guenter J. Krejs, M.D. Rudolph Pointner, M.D. 4 1) Krejs GJ, Seefeld U, Braendli HH, Bron BA, Caro G, Schmid P, Blum AL. Gastro-esophageal reflux disease: Correlation of subjective symptoms with 7 objective esophageal function tests. Acta Hepato-Gastroent 1976; 23:130-140 2) Seefeld U, Krejs GJ, Siebenmann RE, Blum AL. Esophageal histology in gastroesophageal reflux. Morphometric findings in suction biopsies. Am J Dig Dis 1977; 22:956-964

Falk Workshop GERD: Gastroesophageal Reflux Disease Congress Graz Graz, Registration: Wednesday, September 4, 2013 16.00 21.00 h at the congress office Scientific Organization: A. J. Eherer, Graz () G. J. Krejs, Graz () R. Pointner, Zell am See () Information: Guenter J. Krejs, M.D. Professor of Medicine Medical University Graz Division of Gastroenterology and Hepatology Auenbruggerplatz 15 8036 Graz Telephone: + 43(0)316/38513030 Telefax: + 43(0)316/38517560 E-Mail: guenter.krejs@medunigraz.at Congress Venue: Congress Graz Sparkassenplatz 3 8010 Graz Official Language: English. Simultaneous translation into German. 5

Thursday, September 5, 2013 8.45 Welcome G. J. Krejs, Graz Session I Early changes or How does it all start Chair: P. Malfertheiner, Magdeburg; R. Orlando, Chapel Hill 9.00 Epidemiology of GERD G. J. Krejs, Graz 9.30 Esophageal and gastric motility and GERD G. Stacher, Vienna 10.00 Early mucosal changes: Endoscopy F. Schreiber, Graz Histology G. Gorkiewicz, Graz 10.40 Coffee break Session II Medical Therapy Chair: W. Kruis, Cologne; S. J. Spechler, Dallas 11.10 Can withdrawal of PPIs be accomplished? O. B. Schaffalitzky And what if PPIs fail? de Muckadell, Odense 11.40 Helicobacter pylori and GERD P. Malfertheiner, Magdeburg 12.10 Lifestyle modification and alternative approaches A. J. Eherer, (breathing exercise) Graz 12.45 Lunch break 6

Thursday, September 5, 2013 Session III Surgical Aspects Chair: L. Lundell, Stockholm; R. Pointner, Zell am See 13.45 Borderline indications and selection of patients; L. Lundell, Surgery better than medical therapy? Stockholm 14.15 Management of operative failures - R. Pointner, Does endoscopic therapy still have a future? Zell am See 14.45 Esophagitis: Is acid always the problem? F. Hagenmüller, Hamburg 15.15 Does Barrett regress after surgery (or PPIs)? S. J. Spechler, Dallas 15.40 Coffee break Session IV Neoplasia Chair: C. Ell, Wiesbaden; J. Zacherl, Vienna 16.05 Molecular steps to neoplasia in the distal esophagus S. J. Spechler, Dallas 16.35 Endoscopic therapy of early neoplasia C. Ell, Wiesbaden 17.05 How good is the neosquamous epithelium? R. Orlando, Chapel Hill 17.35 Multimodal therapy: Esophageal cancer J. Zacherl, Vienna 17.55 Closing remarks 7

List of Speakers, Moderators and Scientific Organizers Prof. Dr. Andreas J. Eherer Medizinische Universität Graz Klinische Abteilung für Gastroenterologie und Hepatologie Auenbruggerplatz 15 8036 Graz andreas.eherer@medunigraz.at Prof. Dr. Christian Ell Innere Medizin II HSK Dr. Horst Schmidt Klinik Ludwig-Erhard-Str. 102 65199 Wiesbaden Germany christian.ell@hsk-wiesbaden.de Dr. Gregor Gorkiewicz Medizinische Universität Graz Pathologisches Institut Auenbruggerplatz 8 8036 Graz gregor.gorkiewicz@medunigraz.at Prof. Dr. Friedrich Hagenmüller Innere Medizin I Asklepios Klinik Altona Paul-Ehrlich-Str. 1 22763 Hamburg Germany f.hagenmueller@asklepios.com Prof. Dr. Guenter J. Krejs Medizinische Universität Graz Klinische Abteilung für Gastroenterologie und Hepatologie Auenbruggerplatz 15 8036 Graz guenter.krejs@medunigraz.at Prof. Dr. Wolfgang Kruis Innere Medizin Evang. Krankenhaus Kalk Buchforststr. 2 51103 Köln Germany kruis@evkk.de Prof. Dr. Lars Lundell Karolinska University Hospital Huddinge Division of Surgery 141 86 Stockholm Sweden lars.lundell@karolinska.se Prof. Dr. Peter Malfertheiner Gastroenterologie/Hepatologie Universitätsklinikum Otto-von-Guericke-Universität Leipziger Str. 44 39120 Magdeburg Germany peter.malfertheiner@med.ovgu.de Roy Orlando, M.D. Professor of Medicine University of North Carolina Department of Cell and Molecular Physiology 111 Mason Farm Road Chapel Hill NC 27599-7545 USA roy_orlando@med.unc.edu Prof. Dr. Rudolph Pointner Allgemeines öffentliches Krankenhaus Allgemeinchirurgische Abteilung Paracelsusstr. 8 5700 Zell am See rudolph.pointner@kh-zellamsee.at 8

Dr. Ove B. Schaffalitzky de Muckadell Odense University Hospital Biokemisk Institut Research Unit Campusvej 55 5230 Odense Denmark sdm@ouh.regionsyddanmark.dk Prof. Dr. Florian Schreiber Medizinische Universität Graz Klinische Abteilung für Gastroenterologie und Hepatologie Auenbruggerplatz 15 8036 Graz florian.schreiber@medunigraz.at Prof. em. Dr. Georg Stacher Medizinische Universität Wien Psychophysiologisches Labor Währinger Gürtel 18-20 1090 Wien georg.stacher@akh-wien.ac.at Prof. Dr. Johannes Zacherl Medizinische Universität Wien Universitätsklinik für Chirurgie Währinger Gürtel 18-20 1090 Wien johannes.zacherl@meduniwien.ac.at Stuart J. Spechler, M.D. Professor of Medicine VA Medical Center Department of Gastroenterology 4500 S. Lancaster Road Dallas TX 75216-7167 USA sjspechler@aol.com 9

Congress Office During Falk Workshop Telephone: +49(0)175/7795327 Congress Graz Sparkassenplatz 3 8010 Graz Opening Hours: Wednesday, September 4, 2013 Thursday, September 5, 2013 16.00 21.00 h 8.00 21.00 h Congress Fees Scientific program of the Falk Workshop e 100, Students and residents e 50, Employees of pharmaceutical companies and their guests Falk Workshop e 300,- The congress fees include: - Welcome Evening on September 5, 2013 - Refreshments during coffee breaks - Lunch on September 5, 2013 - A copy of the abstract volume 10

Admission to Scientific Events For admission to scientific events your name badge should be clearly visible. Congress Report The official congress report of the Falk Workshop GERD: Gastroesophageal Reflux Disease and Falk Symposium 189 Eosinophilic Esophagitis: A novel chronicinflammatory disease of the GI Tract will be published in English in the first half of 2014 by Karger, Switzerland. Orders for this book at a reduced subscription price of e 35,- can be placed at the Congress Office during the congress in Graz. Hotel Accommodation Hotel reservations can be made online: www.graztourismus.at Airport Airport Graz 11

Innovative Drugs for bowel and liver diseases Modern formulations and specially designed delivery systems ensure targeted release of the active drug Scientific Dialogue in the interest of therapeutic progress Falk Symposia and Workshops over 250 with almost 130,000 international participants since 1967 Continuing medical education seminars over 15,500, attended by morethan 1.2million physicians and patients in Germany alone Comprehensive literature service for healthcare professionals and patients with more than 200 publications www.falkfoundation.org www.drfalkpharma.com Leinenweberstr. 5 79108 Freiburg Germany Tel +49 (0)761/1514-0 Fax +49 (0)761/1514-321 Mail zentrale@drfalkpharma.de

General Information: FALK FOUNDATION e.v. Leinenweberstr. 5 79108 Freiburg Germany Congress Department Telephone: +49(0)761/1514-0 Telefax: +49(0)761/1514-359 E-mail: symposia@falkfoundation.de www.falkfoundation.de P WSGRAZe 1-08/2013/500 Stü