Evaluation of the methodological quality of 218 articles on autologous breast reconstruction

Größe: px
Ab Seite anzeigen:

Download "Evaluation of the methodological quality of 218 articles on autologous breast reconstruction"

Transkript

1 Arbeitsgemeinschaft für ästhetische, Operationsverfahren plastische und in der Evaluation of the methodological quality of 218 articles on autologous breast reconstruction Katherine J Taylor, Ulrike Bussas, Volker Heyl, Hermann Zoche, Alberto Peek, Carolin Nestle-Krämling, Stefanie J Klug GMDS Mannheim, September 7th, 2010 Background AWOGyn intends to establish an S3 Guideline for breast reconstruction. Therefore they need a systematic review of the literature. 1. Step: Evaluation of the epidemiological and statistical quality of the available published articles. 2. Step: Evaluation of the medical data on the surgical methods used. 2 1

2 Background Our tasks: Conduct the literature search Design a method to evaluate the epidemiological soundness of each included article Create a database for extracting the surgical data. 3 Methods Surgical Techniques Investigated The seven surgical techniques of interest were: TRAM (transverse rectus abdominal myocutaneous flap) LADO (latissimus dorsi flap) DIEP (deep inferior epigastric perforator flap) SGAP (superior gluteal artery perforator flap) IGAP (inferior gluteal artery perforator flap) Gracilis perforator Four flap groups in total Rubens flap 4 2

3 Methods Literature Search Key words in the Pubmed search included various combinations of the surgical technique names and breast flap loss, hernia, abdominal wall, bulge, fat necrosis, patient satisfaction, cosmetic results, cost effects and length of stay, and donor site Search was completed in August, No publication date limits were included in the initial search. 5 Methods Inclusion and Exclusion Criteria Inclusion criteria: Study arms must have 20 or more patients each Only studies published in English or German Article must include one of the seven investigated surgical techniques Indication for reconstruction must be mastecomy due to breast cancer LADO technique published after 1970 TRAM technique published after 1982 DIEP and SGAP/IGAP techniques published after 1994 Exclusion criteria: Focus could not be nipple reconstruction, or pain management No animal or cadaver studies No reviews 6 3

4 Methods Preselection based on the abstract Included articles were obtained in full-text and reviewed using the Quality Criteria Check List Created a check list to evaluate included articles: Each article could receive up to 20 points. Quality points were awarded based on 18 quality criteria (two points were possible for two criteria) 7 Methods Quality Criteria Check List Content Points were awarded for information on: 1. study centre 2. timespan study subject recruitment 3. timespan and density of the operations. (2 points awarded if more than 25 patients/year) 4. characteristics of the included study population (eg. ethnicity) 5. statistical power 6. comparison study 7. primary outcomes outlined 8. use of blinding 9. methods to optimize judgement (multiple observations, training) 10.inclusion criteria/study population (2 points possible) 11.differences in baseline characteristics between study arms 12.number of planned examination points 13.statistical methods used explained 14.effect estimates plus confidence intervals or p-values 15. adjusting or stratification 16. selection problems or bias discussed 17.limitations discussed 18. generalizibility discussed 8 4

5 Results Pubmed search Pubmed search: 665 articles Read abstracts Excluded: 379 Included: Results Excluded Abstracts Overview articles: 45 Language: 38 Number of participants too small: 171 Excluded after reading abstracts: 379 Different surgical technique: 54 Different focus: 48 Animal or cadaver experiments: 16 Mixed results not reported separately, only a few patients had cancer, patients included only after complications occurred:

6 Results Abstracts Included Included after reading abstracts: 286 Evaluation of articles using the Check List Excluded: 68 Included: 218 TRAM: 156 * LADO: 55 * DIEP: 33* * SGAP/ IGAP: 4* * * The same article may be represented in more than one group 11 Results Quality Criteria Quality point distribution of the 218 included articles (20 points max.) Number of Articles Quality Score 12 6

7 Background Quality point distribution by surgical method 30 Number of Articles TRAM LADO DIEP SGAP/IGAP Quality Score 13 Results Problems with epidemiological/statistical quality Examples of quality criteria infrequently fulfilled: Statistical power reported: 2% Potential biases discussed: 4% Potential generalizability to other patients discussed: 4% Blinding used: 3% * * Not possible in every study 14 7

8 Conclusion Quality of studies reviewed was low to moderate. Researchers who conduct studies on breast reconstruction could benefit from reviewing basic epidemiological principles and obtaining statistical advice. Checklist provided a fairly objective tool for evaluating articles relative to each other. 15 Current and future plans Articles with 9 or more points will be used for surgical data extraction Number of Articles 67 articles Quality Score 16 8

9 Current and future plans Database was extended to accomodate surgical data from articles Surgical data evaluation and analysis is ongoing 17 Background Thank you for your attention Questions or comments? Katherine J. Taylor: Institute of Medical Biostatistics, Epidemiology and Informatics, University Medical Centre, University of Mainz Ulrike Bussas: Institute of Medical Biostatistics, Epidemiology and Informatics, University Medical Centre, University of Mainz Volker Heyl: Frauenklinik, Asklepios Paulinen Klinik, Wiesbaden Hermann Zoche: Frauenklinik Zentrum für Brusterkrankungen, Klinikum Coburg, Coburg Alberto Peek: Holle & Peek Gemeinschaftspraxis für Plastische Chirurgie, Frankfurt Carolin Nestle-Krämling: Frauenklinik Brustzentrum, Universitätsklinikum Düsseldorf Stefanie J. Klug: Tumour Epidemiology, University Cancer Centre, University Hospital,Technical University of Dresden 18 9

Mitglied der Leibniz-Gemeinschaft

Mitglied der Leibniz-Gemeinschaft Methods of research into dictionary use: online questionnaires Annette Klosa (Institut für Deutsche Sprache, Mannheim) 5. Arbeitstreffen Netzwerk Internetlexikografie, Leiden, 25./26. März 2013 Content

Mehr

Risk of Suicide after Bariatric Surgery

Risk of Suicide after Bariatric Surgery Overview Risk of Suicide after Bariatric Surgery Obesity and Depression Suicidality and Obesity German Obesity-Suicidality Study Birgit Wagner, PhD Department of Psychosomatic Medicine and Psychotherapy

Mehr

Darstellung und Anwendung der Assessmentergebnisse

Darstellung und Anwendung der Assessmentergebnisse Process flow Remarks Role Documents, data, tool input, output Important: Involve as many PZU as possible PZO Start Use appropriate templates for the process documentation Define purpose and scope Define

Mehr

Level 1 German, 2012

Level 1 German, 2012 90886 908860 1SUPERVISOR S Level 1 German, 2012 90886 Demonstrate understanding of a variety of German texts on areas of most immediate relevance 9.30 am Tuesday 13 November 2012 Credits: Five Achievement

Mehr

HIR Method & Tools for Fit Gap analysis

HIR Method & Tools for Fit Gap analysis HIR Method & Tools for Fit Gap analysis Based on a Powermax APML example 1 Base for all: The Processes HIR-Method for Template Checks, Fit Gap-Analysis, Change-, Quality- & Risk- Management etc. Main processes

Mehr

Level 1 German, 2016

Level 1 German, 2016 90886 908860 1SUPERVISOR S Level 1 German, 2016 90886 Demonstrate understanding of a variety of German texts on areas of most immediate relevance 2.00 p.m. Wednesday 23 November 2016 Credits: Five Achievement

Mehr

Level 2 German, 2013

Level 2 German, 2013 91126 911260 2SUPERVISOR S Level 2 German, 2013 91126 Demonstrate understanding of a variety of written and / or visual German text(s) on familiar matters 9.30 am Monday 11 November 2013 Credits: Five

Mehr

PONS DIE DREI??? FRAGEZEICHEN, ARCTIC ADVENTURE: ENGLISCH LERNEN MIT JUSTUS, PETER UND BOB

PONS DIE DREI??? FRAGEZEICHEN, ARCTIC ADVENTURE: ENGLISCH LERNEN MIT JUSTUS, PETER UND BOB Read Online and Download Ebook PONS DIE DREI??? FRAGEZEICHEN, ARCTIC ADVENTURE: ENGLISCH LERNEN MIT JUSTUS, PETER UND BOB DOWNLOAD EBOOK : PONS DIE DREI??? FRAGEZEICHEN, ARCTIC ADVENTURE: Click link bellow

Mehr

EVANGELISCHES GESANGBUCH: AUSGABE FUR DIE EVANGELISCH-LUTHERISCHE LANDESKIRCHE SACHSEN. BLAU (GERMAN EDITION) FROM EVANGELISCHE VERLAGSAN

EVANGELISCHES GESANGBUCH: AUSGABE FUR DIE EVANGELISCH-LUTHERISCHE LANDESKIRCHE SACHSEN. BLAU (GERMAN EDITION) FROM EVANGELISCHE VERLAGSAN EVANGELISCHES GESANGBUCH: AUSGABE FUR DIE EVANGELISCH-LUTHERISCHE LANDESKIRCHE SACHSEN. BLAU (GERMAN EDITION) FROM EVANGELISCHE VERLAGSAN DOWNLOAD EBOOK : EVANGELISCHES GESANGBUCH: AUSGABE FUR DIE EVANGELISCH-LUTHERISCHE

Mehr

Algorithms for graph visualization

Algorithms for graph visualization Algorithms for graph visualization Project - Orthogonal Grid Layout with Small Area W INTER SEMESTER 2013/2014 Martin No llenburg KIT Universita t des Landes Baden-Wu rttemberg und nationales Forschungszentrum

Mehr

A. Wutte, J. Plank, M. Bodenlenz, C. Magnes, W. Regittnig, F. Sinner, B. Rønn, M. Zdravkovic, T. R. Pieber

A. Wutte, J. Plank, M. Bodenlenz, C. Magnes, W. Regittnig, F. Sinner, B. Rønn, M. Zdravkovic, T. R. Pieber Proportional ose Response Relationship and Lower Within Patient Variability of Insulin etemir and NPH Insulin in Subjects With Type 1 iabetes Mellitus A. Wutte, J. Plank, M. Bodenlenz, C. Magnes, W. Regittnig,

Mehr

Level 2 German, 2015

Level 2 German, 2015 91126 911260 2SUPERVISOR S Level 2 German, 2015 91126 Demonstrate understanding of a variety of written and / or visual German text(s) on familiar matters 2.00 p.m. Friday 4 December 2015 Credits: Five

Mehr

Waldwissen.net (Forest-knowledge.net)

Waldwissen.net (Forest-knowledge.net) Waldwissen.net (Forest-knowledge.net) Conference of Directors of State Forest Research Institutes, Vienna, July 5-6th 2004 project idea Establish an internet-based, scientifically sound, comprehensive

Mehr

ONLINE LICENCE GENERATOR

ONLINE LICENCE GENERATOR Index Introduction... 2 Change language of the User Interface... 3 Menubar... 4 Sold Software... 5 Explanations of the choices:... 5 Call of a licence:... 7 Last query step... 9 Call multiple licenses:...

Mehr

Einsatz einer Dokumentenverwaltungslösung zur Optimierung der unternehmensübergreifenden Kommunikation

Einsatz einer Dokumentenverwaltungslösung zur Optimierung der unternehmensübergreifenden Kommunikation Einsatz einer Dokumentenverwaltungslösung zur Optimierung der unternehmensübergreifenden Kommunikation Eine Betrachtung im Kontext der Ausgliederung von Chrysler Daniel Rheinbay Abstract Betriebliche Informationssysteme

Mehr

POST MARKET CLINICAL FOLLOW UP

POST MARKET CLINICAL FOLLOW UP POST MARKET CLINICAL FOLLOW UP (MEDDEV 2.12-2 May 2004) Dr. med. Christian Schübel 2007/47/EG Änderungen Klin. Bewertung Historie: CETF Report (2000) Qualität der klinischen Daten zu schlecht Zu wenige

Mehr

p^db=`oj===pìééçêíáåñçêã~íáçå=

p^db=`oj===pìééçêíáåñçêã~íáçå= p^db=`oj===pìééçêíáåñçêã~íáçå= Error: "Could not connect to the SQL Server Instance" or "Failed to open a connection to the database." When you attempt to launch ACT! by Sage or ACT by Sage Premium for

Mehr

Scenario Building Workshop - Interplay of problem framings

Scenario Building Workshop - Interplay of problem framings Transdiciplinary Conference Inter- and Transdisciplinary Problem Framing, ETH Zürich, 27-28 November 2008 Scenario Building Workshop - Interplay of problem framings PD Dr. Rolf Meyer*, Dr. Martin Knapp*,

Mehr

ISO 15504 Reference Model

ISO 15504 Reference Model Process flow Remarks Role Documents, data, tools input, output Start Define purpose and scope Define process overview Define process details Define roles no Define metrics Pre-review Review yes Release

Mehr

Internationale Energiewirtschaftstagung TU Wien 2015

Internationale Energiewirtschaftstagung TU Wien 2015 Internationale Energiewirtschaftstagung TU Wien 2015 Techno-economic study of measures to increase the flexibility of decentralized cogeneration plants on a German chemical company Luis Plascencia, Dr.

Mehr

CNC ZUR STEUERUNG VON WERKZEUGMASCHINEN (GERMAN EDITION) BY TIM ROHR

CNC ZUR STEUERUNG VON WERKZEUGMASCHINEN (GERMAN EDITION) BY TIM ROHR (GERMAN EDITION) BY TIM ROHR READ ONLINE AND DOWNLOAD EBOOK : CNC ZUR STEUERUNG VON WERKZEUGMASCHINEN (GERMAN EDITION) BY TIM ROHR PDF Click button to download this ebook READ ONLINE AND DOWNLOAD CNC ZUR

Mehr

Grade 12: Qualifikationsphase. My Abitur

Grade 12: Qualifikationsphase. My Abitur Grade 12: Qualifikationsphase My Abitur Qualifikationsphase Note 1 Punkte Prozente Note 1 15 14 13 85 % 100 % Note 2 12 11 10 70 % 84 % Note 3 9 8 7 55 % 69 % Note 4 6 5 4 40 % 54 % Note 5 3 2 1 20 % 39

Mehr

Climate change and availability of water resources for Lima

Climate change and availability of water resources for Lima Climate change and availability of water resources for Lima András Bárdossy bardossy@iws.uni-stuttgart.de Lima Marzo 12. 2009 1 Engineers and the future Knowledge about Past Design for Future Lima Marzo

Mehr

LiLi. physik multimedial. Links to e-learning content for physics, a database of distributed sources

LiLi. physik multimedial. Links to e-learning content for physics, a database of distributed sources physik multimedial Lehr- und Lernmodule für das Studium der Physik als Nebenfach Links to e-learning content for physics, a database of distributed sources Julika Mimkes: mimkes@uni-oldenburg.de Overview

Mehr

ETHISCHES ARGUMENTIEREN IN DER SCHULE: GESELLSCHAFTLICHE, PSYCHOLOGISCHE UND PHILOSOPHISCHE GRUNDLAGEN UND DIDAKTISCHE ANSTZE (GERMAN

ETHISCHES ARGUMENTIEREN IN DER SCHULE: GESELLSCHAFTLICHE, PSYCHOLOGISCHE UND PHILOSOPHISCHE GRUNDLAGEN UND DIDAKTISCHE ANSTZE (GERMAN ETHISCHES ARGUMENTIEREN IN DER SCHULE: GESELLSCHAFTLICHE, PSYCHOLOGISCHE UND PHILOSOPHISCHE GRUNDLAGEN UND DIDAKTISCHE ANSTZE (GERMAN READ ONLINE AND DOWNLOAD EBOOK : ETHISCHES ARGUMENTIEREN IN DER SCHULE:

Mehr

predicts their driving performance?

predicts their driving performance? Does older driver s psychophysical fitness predicts their driving performance? Dr. Tina Gehlert Head of Traffic Behaviour / Traffic Psychology, Accident Research Department, German Insurance Association

Mehr

Fluid-Particle Multiphase Flow Simulations for the Study of Sand Infiltration into Immobile Gravel-Beds

Fluid-Particle Multiphase Flow Simulations for the Study of Sand Infiltration into Immobile Gravel-Beds 3rd JUQUEEN Porting and Tuning Workshop Jülich, 2-4 February 2015 Fluid-Particle Multiphase Flow Simulations for the Study of Sand Infiltration into Immobile Gravel-Beds Tobias Schruff, Roy M. Frings,

Mehr

Which data and when?

Which data and when? PRO-data for market access in Germany where and when? Frank-Ulrich Fricke PRO-data for market access in Germany where and when? AMNOG the German assessment Which data and when? Requirements to be met Seite

Mehr

Concept for the development of an ecological network in Germany. Dr. Rüdiger Burkhardt Landesamt für Umwelt, Wasserwirtschaft und Gewerbeaufsicht

Concept for the development of an ecological network in Germany. Dr. Rüdiger Burkhardt Landesamt für Umwelt, Wasserwirtschaft und Gewerbeaufsicht Concept for the development of an ecological network in Germany Dr. Rüdiger Burkhardt Landesamt für Umwelt, Wasserwirtschaft und Gewerbeaufsicht Topics German Federal Conservation Act Guidelines for the

Mehr

AS Path-Prepending in the Internet And Its Impact on Routing Decisions

AS Path-Prepending in the Internet And Its Impact on Routing Decisions (SEP) Its Impact on Routing Decisions Zhi Qi ytqz@mytum.de Advisor: Wolfgang Mühlbauer Lehrstuhl für Netzwerkarchitekturen Background Motivation BGP -> core routing protocol BGP relies on policy routing

Mehr

VGM. VGM information. HAMBURG SÜD VGM WEB PORTAL - USER GUIDE June 2016

VGM. VGM information. HAMBURG SÜD VGM WEB PORTAL - USER GUIDE June 2016 Overview The Hamburg Süd VGM-Portal is an application which enables to submit VGM information directly to Hamburg Süd via our e-portal web page. You can choose to insert VGM information directly, or download

Mehr

Context-adaptation based on Ontologies and Spreading Activation

Context-adaptation based on Ontologies and Spreading Activation -1- Context-adaptation based on Ontologies and Spreading Activation ABIS 2007, Halle, 24.09.07 {hussein,westheide,ziegler}@interactivesystems.info -2- Context Adaptation in Spreadr Pubs near my location

Mehr

SCHNELLES DENKEN, LANGSAMES DENKEN (GERMAN EDITION) BY DANIEL KAHNEMAN

SCHNELLES DENKEN, LANGSAMES DENKEN (GERMAN EDITION) BY DANIEL KAHNEMAN Read Online and Download Ebook SCHNELLES DENKEN, LANGSAMES DENKEN (GERMAN EDITION) BY DANIEL KAHNEMAN DOWNLOAD EBOOK : SCHNELLES DENKEN, LANGSAMES DENKEN (GERMAN Click link bellow and free register to

Mehr

Exercise (Part XI) Anastasia Mochalova, Lehrstuhl für ABWL und Wirtschaftsinformatik, Kath. Universität Eichstätt-Ingolstadt 1

Exercise (Part XI) Anastasia Mochalova, Lehrstuhl für ABWL und Wirtschaftsinformatik, Kath. Universität Eichstätt-Ingolstadt 1 Exercise (Part XI) Notes: The exercise is based on Microsoft Dynamics CRM Online. For all screenshots: Copyright Microsoft Corporation. The sign ## is you personal number to be used in all exercises. All

Mehr

FIVNAT-CH. Annual report 2002

FIVNAT-CH. Annual report 2002 FIVNAT-CH Schweizerische Gesellschaft für Reproduktionsmedizin Annual report 2002 Date of analysis 15.01.2004 Source: FileMaker Pro files FIVNAT_CYC.FP5 and FIVNAT_PAT.FP5 SUMMARY TABLE SUMMARY RESULTS

Mehr

ELBA2 ILIAS TOOLS AS SINGLE APPLICATIONS

ELBA2 ILIAS TOOLS AS SINGLE APPLICATIONS ELBA2 ILIAS TOOLS AS SINGLE APPLICATIONS An AAA/Switch cooperative project run by LET, ETH Zurich, and ilub, University of Bern Martin Studer, ilub, University of Bern Julia Kehl, LET, ETH Zurich 1 Contents

Mehr

Einladung zum CFE Exam Review Course in Zürich Mai 2016

Einladung zum CFE Exam Review Course in Zürich Mai 2016 Association of Certified Fraud Examiners Switzerland Chapter # 104 Zürich, 9. November 2015 English version further down Einladung zum CFE Exam Review Course in Zürich Mai 2016 Sehr geehrte Mitglieder,

Mehr

Presentation of a diagnostic tool for hybrid and module testing

Presentation of a diagnostic tool for hybrid and module testing Presentation of a diagnostic tool for hybrid and module testing RWTH Aachen III. Physikalisches Institut B M.Axer, F.Beißel, C.Camps, V.Commichau, G.Flügge, K.Hangarter, J.Mnich, P.Schorn, R.Schulte, W.

Mehr

NEWSLETTER. FileDirector Version 2.5 Novelties. Filing system designer. Filing system in WinClient

NEWSLETTER. FileDirector Version 2.5 Novelties. Filing system designer. Filing system in WinClient Filing system designer FileDirector Version 2.5 Novelties FileDirector offers an easy way to design the filing system in WinClient. The filing system provides an Explorer-like structure in WinClient. The

Mehr

LEBEN OHNE REUE: 52 IMPULSE, DIE UNS DARAN ERINNERN, WAS WIRKLICH WICHTIG IST (GERMAN EDITION) BY BRONNIE WARE

LEBEN OHNE REUE: 52 IMPULSE, DIE UNS DARAN ERINNERN, WAS WIRKLICH WICHTIG IST (GERMAN EDITION) BY BRONNIE WARE LEBEN OHNE REUE: 52 IMPULSE, DIE UNS DARAN ERINNERN, WAS WIRKLICH WICHTIG IST (GERMAN EDITION) BY BRONNIE WARE DOWNLOAD EBOOK : LEBEN OHNE REUE: 52 IMPULSE, DIE UNS DARAN EDITION) BY BRONNIE WARE PDF Click

Mehr

HUMANGENETIK IN DER WELT VON HEUTE: 12 SALZBURGER VORLESUNGEN (GERMAN EDITION) BY FRIEDRICH VOGEL

HUMANGENETIK IN DER WELT VON HEUTE: 12 SALZBURGER VORLESUNGEN (GERMAN EDITION) BY FRIEDRICH VOGEL FRIEDRICH VOGEL READ ONLINE AND DOWNLOAD EBOOK : HUMANGENETIK IN DER WELT VON HEUTE: 12 SALZBURGER VORLESUNGEN (GERMAN EDITION) BY Click button to download this ebook READ ONLINE AND DOWNLOAD HUMANGENETIK

Mehr

Prof. Dr. Margit Scholl, Mr. RD Guldner Mr. Coskun, Mr. Yigitbas. Mr. Niemczik, Mr. Koppatz (SuDiLe GbR)

Prof. Dr. Margit Scholl, Mr. RD Guldner Mr. Coskun, Mr. Yigitbas. Mr. Niemczik, Mr. Koppatz (SuDiLe GbR) Prof. Dr. Margit Scholl, Mr. RD Guldner Mr. Coskun, Mr. Yigitbas in cooperation with Mr. Niemczik, Mr. Koppatz (SuDiLe GbR) Our idea: Fachbereich Wirtschaft, Verwaltung und Recht Simple strategies of lifelong

Mehr

Medizinische Klinik II Medizinische Klinik IV

Medizinische Klinik II Medizinische Klinik IV CAMPUS GROSSHADERN CAMPUS INNENSTADT LOREM IPSUM SETUR ALARME Medizinische Klinik II Medizinische Klinik IV Effect of Mipomersen on LDL-Cholesterol levels in Patients with Severe LDL-Hypercholesterolemia

Mehr

LEBEN OHNE REUE: 52 IMPULSE, DIE UNS DARAN ERINNERN, WAS WIRKLICH WICHTIG IST (GERMAN EDITION) BY BRONNIE WARE

LEBEN OHNE REUE: 52 IMPULSE, DIE UNS DARAN ERINNERN, WAS WIRKLICH WICHTIG IST (GERMAN EDITION) BY BRONNIE WARE Read Online and Download Ebook LEBEN OHNE REUE: 52 IMPULSE, DIE UNS DARAN ERINNERN, WAS WIRKLICH WICHTIG IST (GERMAN EDITION) BY BRONNIE WARE DOWNLOAD EBOOK : LEBEN OHNE REUE: 52 IMPULSE, DIE UNS DARAN

Mehr

slides alcohol prk.wmv

slides alcohol prk.wmv Pain and functioning post Alcohol PRK vs. -PRK: A prospective Intra-individual Comparison Toam Katz, Gisbert Richard, S. J. Linke Subjektive Entwicklung der Schmerzsymptomatik und Funktion nach Alcohol

Mehr

TMF projects on IT infrastructure for clinical research

TMF projects on IT infrastructure for clinical research Welcome! TMF projects on IT infrastructure for clinical research R. Speer Telematikplattform für Medizinische Forschungsnetze (TMF) e.v. Berlin Telematikplattform für Medizinische Forschungsnetze (TMF)

Mehr

Workflows, Ansprüche und Grenzen der GNSS- Datenerfassung im Feld

Workflows, Ansprüche und Grenzen der GNSS- Datenerfassung im Feld Workflows, Ansprüche und Grenzen der GNSS- Datenerfassung im Feld Alexander Fischer Senior Application Engineer Asset Collection & GIS 1 Leica Zeno GIS Agenda Erfassung im Feld VS Erfassung im Office Validierung

Mehr

Antragsverfahren. Katerina Kotzia, SusAn Call Secretariat

Antragsverfahren. Katerina Kotzia, SusAn Call Secretariat Antragsverfahren Katerina Kotzia, SusAn Call Secretariat Zeitschiene Aktivitäten Termine Launch of the Co-funded Call 04.01.2016 First step: submission of pre-proposals Deadline for pre-proposal submission

Mehr

ISO 15504 Reference Model

ISO 15504 Reference Model Prozess Dimension von SPICE/ISO 15504 Process flow Remarks Role Documents, data, tools input, output Start Define purpose and scope Define process overview Define process details Define roles no Define

Mehr

eurex rundschreiben 094/10

eurex rundschreiben 094/10 eurex rundschreiben 094/10 Datum: Frankfurt, 21. Mai 2010 Empfänger: Alle Handelsteilnehmer der Eurex Deutschland und Eurex Zürich sowie Vendoren Autorisiert von: Jürg Spillmann Weitere Informationen zur

Mehr

Exercise (Part II) Anastasia Mochalova, Lehrstuhl für ABWL und Wirtschaftsinformatik, Kath. Universität Eichstätt-Ingolstadt 1

Exercise (Part II) Anastasia Mochalova, Lehrstuhl für ABWL und Wirtschaftsinformatik, Kath. Universität Eichstätt-Ingolstadt 1 Exercise (Part II) Notes: The exercise is based on Microsoft Dynamics CRM Online. For all screenshots: Copyright Microsoft Corporation. The sign ## is you personal number to be used in all exercises. All

Mehr

TomTom WEBFLEET Tachograph

TomTom WEBFLEET Tachograph TomTom WEBFLEET Tachograph Installation TG, 17.06.2013 Terms & Conditions Customers can sign-up for WEBFLEET Tachograph Management using the additional services form. Remote download Price: NAT: 9,90.-/EU:

Mehr

Sofortige Beckenbodenrekonstruktion mit einem Rektus abdominis Lappen ( VRAM) nach abdominoperinealer Rektumamputation bei Rektum- und Analkarzinom

Sofortige Beckenbodenrekonstruktion mit einem Rektus abdominis Lappen ( VRAM) nach abdominoperinealer Rektumamputation bei Rektum- und Analkarzinom Rekonstruktive Mikrochirurgie Handchirurgie Ästhetische Chirurgie Verbrennungschirurgie Möglichkeiten der plastischen Chirurgie beim kolorektalen Karzinom M. Geomelas 1, W. Rau 2, M. Ghods 1 1 Klinik für

Mehr

August Macke 1887-1914 Abschied, 1914 Museum Ludwig, Köln

August Macke 1887-1914 Abschied, 1914 Museum Ludwig, Köln August Macke 1887-1914 Abschied, 1914 Museum Ludwig, Köln Ideas for the classroom 1. Introductory activity wer?, was?, wo?, wann?, warum? 2. Look at how people say farewell in German. 3. Look at how people

Mehr

Challenges for the future between extern and intern evaluation

Challenges for the future between extern and intern evaluation Evaluation of schools in switzerland Challenges for the future between extern and intern evaluation Michael Frais Schulentwicklung in the Kanton Zürich between internal evaluation and external evaluation

Mehr

Mark Scheme (Results) Summer 2007

Mark Scheme (Results) Summer 2007 Mark Scheme (Results) Summer 2007 GCSE GCSE German (1231) Paper 4F Edexcel Limited. Registered in England and Wales No. 4496750 Registered Office: One90 High Holborn, London WC1V 7BH Paper 4F Mark Scheme

Mehr

Mensch-Maschine-Interaktion 2 Übung 1

Mensch-Maschine-Interaktion 2 Übung 1 Mensch-Maschine-Interaktion 2 Übung 1 Ludwig-Maximilians-Universität München Wintersemester 2012/2013 Alexander De Luca, Aurélien Tabard Ludwig-Maximilians-Universität München Mensch-Maschine-Interaktion

Mehr

SOEP-IS 2013 BIOBRTHM: Birth Biography of Male Respondents*

SOEP-IS 2013 BIOBRTHM: Birth Biography of Male Respondents* SOEP-IS 2013 BIOBRTHM: Birth Biography of Male Respondents* SOEP-IS Group 2015-07-10 DIW/SOEP, Berlin *This file is part of a collection, which is released with doi:10.5684/soep.is.2013 Inhaltsverzeichnis

Mehr

Software development with continuous integration

Software development with continuous integration Software development with continuous integration (FESG/MPIfR) ettl@fs.wettzell.de (FESG) neidhardt@fs.wettzell.de 1 A critical view on scientific software Tendency to become complex and unstructured Highly

Mehr

Einführung Physiotherapie

Einführung Physiotherapie Einführung Physiotherapie Was können Physiotherapeuten außer massieren? 29.08.166 Cologne Dr. rer. medic. Christina Stark PT M.Sc. Klinik und Poliklinik für Kinder- und Jugendmedizin Lernziele Nach Abschluss

Mehr

Eingebettete Taktübertragung auf Speicherbussen

Eingebettete Taktübertragung auf Speicherbussen Eingebettete Taktübertragung auf Speicherbussen Johannes Reichart Workshop Hochgeschwindigkeitsschnittstellen Stuttgart, 07.11.2008 Unterstützt durch: Qimonda AG, München Institut für Prof. Elektrische

Mehr

Systematische Übersichtsarbeit zu gesundheitsökonomischen Evaluationen im Kontext der Behandlung und Prävention der Adipositas

Systematische Übersichtsarbeit zu gesundheitsökonomischen Evaluationen im Kontext der Behandlung und Prävention der Adipositas Systematische Übersichtsarbeit zu gesundheitsökonomischen Evaluationen im Kontext der Behandlung und Prävention der Adipositas Schwander B (1, 2), Hiligsmann M (1), Nuijten M (1,3), Evers S (1) (1) CAPHRI

Mehr

Meteorological measurements at the Offshore Platform FINO 2 - new insights -

Meteorological measurements at the Offshore Platform FINO 2 - new insights - FINO 2011 Conference May 11 th 2011, Hamburg, Germany Meteorological measurements at the Offshore Platform FINO 2 - new insights - Dipl.-Geoök. Stefan Müller, Dipl.-Ing Joachim Schwabe Content 1. FINO

Mehr

Level of service estimation at traffic signals based on innovative traffic data services and collection techniques

Level of service estimation at traffic signals based on innovative traffic data services and collection techniques Level of service estimation at traffic signals based on innovative traffic data services and collection techniques Authors: Steffen Axer, Jannis Rohde, Bernhard Friedrich Network-wide LOS estimation at

Mehr

Simulation of a Battery Electric Vehicle

Simulation of a Battery Electric Vehicle Simulation of a Battery Electric Vehicle M. Auer, T. Kuthada, N. Widdecke, J. Wiedemann IVK/FKFS University of Stuttgart 1 2.1.214 Markus Auer Agenda Motivation Thermal Management for BEV Simulation Model

Mehr

How does the Institute for quality and efficiency in health care work?

How does the Institute for quality and efficiency in health care work? Health Care for all Creating Effective and Dynamic Structures How does the Institute for quality and efficiency in health care work? Peter T. Sawicki; Institute for Quality and Efficiency in Health Care.

Mehr

The process runs automatically and the user is guided through it. Data acquisition and the evaluation are done automatically.

The process runs automatically and the user is guided through it. Data acquisition and the evaluation are done automatically. Q-App: UserCal Advanced Benutzerdefinierte Kalibrierroutine mit Auswertung über HTML (Q-Web) User defined calibration routine with evaluation over HTML (Q-Web) Beschreibung Der Workflow hat 2 Ebenen eine

Mehr

LEBEN OHNE REUE: 52 IMPULSE, DIE UNS DARAN ERINNERN, WAS WIRKLICH WICHTIG IST (GERMAN EDITION) BY BRONNIE WARE

LEBEN OHNE REUE: 52 IMPULSE, DIE UNS DARAN ERINNERN, WAS WIRKLICH WICHTIG IST (GERMAN EDITION) BY BRONNIE WARE Read Online and Download Ebook LEBEN OHNE REUE: 52 IMPULSE, DIE UNS DARAN ERINNERN, WAS WIRKLICH WICHTIG IST (GERMAN EDITION) BY BRONNIE WARE DOWNLOAD EBOOK : LEBEN OHNE REUE: 52 IMPULSE, DIE UNS DARAN

Mehr

Tuesday 10 May 2011 Afternoon Time: 30 minutes plus 5 minutes reading time

Tuesday 10 May 2011 Afternoon Time: 30 minutes plus 5 minutes reading time Write your name here Surname Other names Edexcel IGCSE German Paper 1: Listening Centre Number Candidate Number Tuesday 10 May 2011 Afternoon Time: 30 minutes plus 5 minutes reading time You do not need

Mehr

Efficient Design Space Exploration for Embedded Systems

Efficient Design Space Exploration for Embedded Systems Diss. ETH No. 16589 Efficient Design Space Exploration for Embedded Systems A dissertation submitted to the SWISS FEDERAL INSTITUTE OF TECHNOLOGY ZURICH for the degree of Doctor of Sciences presented by

Mehr

Making quality visible. National Quality Certificate for Old Age and Nursing Homes in Austria (NQC)

Making quality visible. National Quality Certificate for Old Age and Nursing Homes in Austria (NQC) Making quality visible. National Quality Certificate for Old Age and Nursing Homes in Austria (NQC) Human Rights Council Genf, 15 September 2015 The Austrian System of Long Term Care System: 2 main components:

Mehr

BACK TO BLACK: AMY WINEHOUSE UND IHR VIEL ZU KURZES LEBEN (GERMAN EDITION) BY ALEXANDER SCHULLER, NICOLE VON BREDOW

BACK TO BLACK: AMY WINEHOUSE UND IHR VIEL ZU KURZES LEBEN (GERMAN EDITION) BY ALEXANDER SCHULLER, NICOLE VON BREDOW SCHULLER, NICOLE VON BREDOW READ ONLINE AND DOWNLOAD EBOOK : BACK TO BLACK: AMY WINEHOUSE UND IHR VIEL ZU KURZES LEBEN (GERMAN EDITION) BY ALEXANDER SCHULLER, NICOLE VON BREDOW PDF Click button to download

Mehr

Quality Management is Ongoing Social Innovation Hans-Werner Franz

Quality Management is Ongoing Social Innovation Hans-Werner Franz Quality Management is Ongoing Social Innovation Hans-Werner Franz ICICI Conference, Prague 1-2 October 2009 What I am going to tell you social innovation the EFQM Excellence model the development of quality

Mehr

Zertifikate: Nutzen für wen?

Zertifikate: Nutzen für wen? Zertifikate: Nutzen für wen? Zertifikate = Bessere Qualität? Hans Ulrich Rothen, Vorsitzender Qualitätskommission Inselspital Zertifizierungen Überprüfung von Prozessen (Arbeitsabläufen) und deren Ergebnisse

Mehr

GIS-based Mapping Tool for Urban Energy Demand

GIS-based Mapping Tool for Urban Energy Demand GIS-based Mapping Tool for Urban Energy Demand Building Services, Mechanical and Building Industry Days Conference Johannes Dorfner Debrecen, 14 October 2011 Outline 1. Motivation 2. Method 3. Result 4.

Mehr

Possible Contributions to Subtask B Quality Procedure

Possible Contributions to Subtask B Quality Procedure Possible Contributions to Subtask B Quality Procedure aeteba - Energy Systems, Germany Elmar Sporer zafh.net Stuttgart, Germany Dr. Dirk Pietruschka 1/14 aeteba - Consortium of different companies - Turnkey

Mehr

Support Technologies based on Bi-Modal Network Analysis. H. Ulrich Hoppe. Virtuelles Arbeiten und Lernen in projektartigen Netzwerken

Support Technologies based on Bi-Modal Network Analysis. H. Ulrich Hoppe. Virtuelles Arbeiten und Lernen in projektartigen Netzwerken Support Technologies based on Bi-Modal Network Analysis H. Agenda 1. Network analysis short introduction 2. Supporting the development of virtual organizations 3. Supporting the development of compentences

Mehr

Approx. 2,000 frontlist books and 18,000 backlist books; list will be updated periodically

Approx. 2,000 frontlist books and 18,000 backlist books; list will be updated periodically This checklist provides an overview of the fees and features of the e-books and some additional details. This will simplify the evaluation of the product for the consortia partners. Checklist for e-books

Mehr

VICTOR STRINGING PATTERN 72-HOLES. Starting Point lengthwise. Ending cross point (C6)

VICTOR STRINGING PATTERN 72-HOLES.  Starting Point lengthwise. Ending cross point (C6) VICTOR STRINGING PATTERN 72-HOLES Starting Point lengthwise Ending cross point (C6) C6 Tie off cross after two cross lines. Starting Point cross (B8) VICTOR STRINGING PATTERN 76-HOLES Starting Point lengthwise

Mehr

JPlus Platform Independent Learning with Environmental Information in School

JPlus Platform Independent Learning with Environmental Information in School JPlus Platform Independent Learning with Environmental Information in School Mario Härtwig, Pierre Karrasch Salzburg, 7. Juli 2010 Genesis Umweltmonitoring als Beitrag zur Umweltbildung an Schulen. Kulturlandschaftsentwicklung

Mehr

German Geography Cookie Unit Haley Crittenden Gordon German Teacher Lee High School & Key Middle School (adapted from Angelika Becker)

German Geography Cookie Unit Haley Crittenden Gordon German Teacher Lee High School & Key Middle School (adapted from Angelika Becker) German Geography Cookie Unit Haley Crittenden Gordon German Teacher Lee High School & Key Middle School (adapted from Angelika Becker) Goal Students will learn about the physical geography of Germany,

Mehr

Der Wetterbericht für Deutschland. Read the weather reports and draw the correct weather symbols for each town.

Der Wetterbericht für Deutschland. Read the weather reports and draw the correct weather symbols for each town. Der Wetterbericht für Deutschland Read the weather reports and draw the correct weather symbols for each town. Es ist sehr heiß in Berlin und es donnert und blitzt in Frankfurt. Es ist ziemlich neblig

Mehr

Introducing PAThWay. Structured and methodical performance engineering. Isaías A. Comprés Ureña Ventsislav Petkov Michael Firbach Michael Gerndt

Introducing PAThWay. Structured and methodical performance engineering. Isaías A. Comprés Ureña Ventsislav Petkov Michael Firbach Michael Gerndt Introducing PAThWay Structured and methodical performance engineering Isaías A. Comprés Ureña Ventsislav Petkov Michael Firbach Michael Gerndt Technical University of Munich Overview Tuning Challenges

Mehr

Country fact sheet. Noise in Europe overview of policy-related data. Germany

Country fact sheet. Noise in Europe overview of policy-related data. Germany Country fact sheet Noise in Europe 2015 overview of policy-related data Germany April 2016 The Environmental Noise Directive (END) requires EU Member States to assess exposure to noise from key transport

Mehr

Corporate Digital Learning, How to Get It Right. Learning Café

Corporate Digital Learning, How to Get It Right. Learning Café 0 Corporate Digital Learning, How to Get It Right Learning Café Online Educa Berlin, 3 December 2015 Key Questions 1 1. 1. What is the unique proposition of digital learning? 2. 2. What is the right digital

Mehr

STRATEGISCHES BETEILIGUNGSCONTROLLING BEI KOMMUNALEN UNTERNEHMEN DER FFENTLICHE ZWECK ALS RICHTSCHNUR FR EIN ZIELGERICHTETE

STRATEGISCHES BETEILIGUNGSCONTROLLING BEI KOMMUNALEN UNTERNEHMEN DER FFENTLICHE ZWECK ALS RICHTSCHNUR FR EIN ZIELGERICHTETE BETEILIGUNGSCONTROLLING BEI KOMMUNALEN UNTERNEHMEN DER FFENTLICHE ZWECK ALS RICHTSCHNUR FR EIN ZIELGERICHTETE PDF-SBBKUDFZARFEZ41-APOM3 123 Page File Size 5,348 KB 3 Feb, 2002 TABLE OF CONTENT Introduction

Mehr

STRATEGISCHES BETEILIGUNGSCONTROLLING BEI KOMMUNALEN UNTERNEHMEN DER FFENTLICHE ZWECK ALS RICHTSCHNUR FR EIN ZIELGERICHTETE

STRATEGISCHES BETEILIGUNGSCONTROLLING BEI KOMMUNALEN UNTERNEHMEN DER FFENTLICHE ZWECK ALS RICHTSCHNUR FR EIN ZIELGERICHTETE BETEILIGUNGSCONTROLLING BEI KOMMUNALEN UNTERNEHMEN DER FFENTLICHE ZWECK ALS RICHTSCHNUR FR EIN ZIELGERICHTETE PDF-SBBKUDFZARFEZ41-SEOM3 123 Page File Size 5,348 KB 3 Feb, 2002 TABLE OF CONTENT Introduction

Mehr

Pilot Project Biogas-powered Micro-gas-turbine

Pilot Project Biogas-powered Micro-gas-turbine 1/18 Pilot Project Biogas-powered Micro-gas-turbine Supported by the Hessischen Ministerium für Wirtschaft, Verkehr und Landesentwicklung Speaker Details 2/18 Jan Müller Works at Institute of Solar Energy

Mehr

Environmental management in German institutions of higher education: Lessons learnt and steps toward sustainable management

Environmental management in German institutions of higher education: Lessons learnt and steps toward sustainable management Environmental management in German institutions of higher education: Lessons learnt and steps toward sustainable management Lüneburg, Juni 23/24, 2005 Joachim Müller Sustainable Management of Higher Education

Mehr

DIE NEUORGANISATION IM BEREICH DES SGB II AUSWIRKUNGEN AUF DIE ZUSAMMENARBEIT VON BUND LNDERN UND KOMMUNEN

DIE NEUORGANISATION IM BEREICH DES SGB II AUSWIRKUNGEN AUF DIE ZUSAMMENARBEIT VON BUND LNDERN UND KOMMUNEN DIE NEUORGANISATION IM BEREICH DES SGB II AUSWIRKUNGEN AUF DIE ZUSAMMENARBEIT VON BUND LNDERN UND KOMMUNEN WWOM537-PDFDNIBDSIAADZVBLUK 106 Page File Size 4,077 KB 16 Feb, 2002 COPYRIGHT 2002, ALL RIGHT

Mehr

Redress Procedure in Horizont 2020

Redress Procedure in Horizont 2020 Redress Procedure in Horizont 2020 Informationen zur Redress Procedure sind im Teilnehmerportal unter folgendem Link zu finden: https://webgate.ec.europa.eu/redress-frontoffice/work.iface Die Anmeldung

Mehr

How to develop and improve the functioning of the audit committee The Auditor s View

How to develop and improve the functioning of the audit committee The Auditor s View How to develop and improve the functioning of the audit committee The Auditor s View May 22, 2013 Helmut Kerschbaumer KPMG Austria Audit Committees in Austria Introduced in 2008, applied since 2009 Audit

Mehr

European Qualification Strategies in Information and Communications Technology (ICT)

European Qualification Strategies in Information and Communications Technology (ICT) European Qualification Strategies in Information and Communications Technology (ICT) Towards a European (reference) ICT Skills and Qualification Framework Results and Recommendations from the Leornardo-da-Vinci-II

Mehr

Meeting and TASK TOOL. Bedienungsanleitung / Manual. 2010 IQxperts GmbH. Alle Rechte vorbehalten.

Meeting and TASK TOOL. Bedienungsanleitung / Manual. 2010 IQxperts GmbH. Alle Rechte vorbehalten. 2010 IQxperts GmbH. Alle Rechte vorbehalten. Weitergabe und Vervielfältigung dieser Publikation oder von Teilen daraus sind, zu welchem Zweck und in welcher Form auch immer, ohne die ausdrückliche schriftliche

Mehr

Tools in a Clinical Information System Supporting Clinical Trials at a Swiss University Hospital (Clin Trials, published online 12 August 2014)

Tools in a Clinical Information System Supporting Clinical Trials at a Swiss University Hospital (Clin Trials, published online 12 August 2014) ehealth Summit 2014, Bern Tools in a Clinical Information System Supporting Clinical Trials at a Swiss University Hospital (Clin Trials, published online 12 August 2014) Dr. med. Michael Weisskopf Forschungszentrum

Mehr

COSMOS-Portal - Benutzerhandbuch

COSMOS-Portal - Benutzerhandbuch COSMOS-Portal - Benutzerhandbuch Erstellt von: Christian Reimers Version: draft1 (Nov. 2008) Inhaltsverzeichnis Erste Schritte Startseite des COSMOS Portals Registrierung Anmeldung (Log in) Reiter Home

Mehr

Ways and methods to secure customer satisfaction at the example of a building subcontractor

Ways and methods to secure customer satisfaction at the example of a building subcontractor Abstract The thesis on hand deals with customer satisfaction at the example of a building subcontractor. Due to the problems in the building branch, it is nowadays necessary to act customer oriented. Customer

Mehr

Applying Pléiades in the ASAP project HighSens

Applying Pléiades in the ASAP project HighSens Applying Pléiades in the ASAP project HighSens Highly versatile, new satellite Sensor applications for the Austrian market and International Development (Contract number: 833435) Dr. Eva Haas, GeoVille

Mehr

Journal: Journal of Clinical Oncology Publikationsjahr: 2012 Autoren: Paulo M. Hoff, Andreas Hochhaus, Bernhard C. Pestalozzi et al.

Journal: Journal of Clinical Oncology Publikationsjahr: 2012 Autoren: Paulo M. Hoff, Andreas Hochhaus, Bernhard C. Pestalozzi et al. Cediranib Plus FOLFOX/CAPOX Versus Placebo Plus FOLFOX/CAPOX in Patients With Previously Untreated Metastatic Colorectal Cancer: A Randomized, Double Blind, Phase III Study (HORIZON II) Journal: Journal

Mehr

Exploring the knowledge in Semi Structured Data Sets with Rich Queries

Exploring the knowledge in Semi Structured Data Sets with Rich Queries Exploring the knowledge in Semi Structured Data Sets with Rich Queries Jürgen Umbrich Sebastian Blohm Institut AIFB, Universität Karlsruhe (TH) Forschungsuniversität gegründet 1825 www.kit.ed Overview

Mehr