Preliminary Program. Carcinogenesis, Prevention and Treatment of Colorectal Cancer State-of-the-Art 2012. Falk Symposium 182



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Falk Symposium 182 Carcinogenesis, Prevention and Treatment of Colorectal Cancer State-of-the-Art 2012 February 10 11, 2012 The Westin Grand Hotel Munich, Jointly co-organized with the ICRCC Preliminary Program Application for CME credits submitted

Preface... 4 Scientific Program......................... 6 Posters... 11 List of Speakers... 12 Information... 18 CME credits for the Falk Symposium 182 have been applied for at the European Union of Medical Specialists (UEMS) European Board of Gastroenterology (EBG). The number of credits awarded will be printed in the final program. 3

Preface The World Health Organization (WHO) reported more than 600,000 deaths due to colorectal cancer in 2008 worldwide. The majority of these cancers could be prevented by the wide use of existing knowledge on cancer prevention, established screening methods and the use of modern treatment modalities. Since most colorectal cancers develop from adenomatous polyps, most cancers could be prevented by screening colonoscopies. The current understanding of carcinogenesis in colorectal cancer has led to improved diagnostic and therapeutic tools, which increase the probability of long-term survival of colorectal cancer. Major improvements have been achieved in endoscopy, surgery, chemotherapy and radio-oncology over the last years. Therefore, all colorectal cancer patients should be discussed in interdisciplinary tumor boards to determine the best individualized treatment plan, based on current knowledge in each clinical specialty. The aim of this international symposium Carcinogenesis, Prevention and Treatment of Colorectal Cancer State of the Art 2012 is to discuss the up-to-date colorectal cancer knowledge with basic and clinical researchers, general practitioners and colorectal cancer specialists in a wide interdisciplinary setting. We expect the participation of a high number of renowned experts from all over the world to increase our knowledge about colorectal cancer in regard to our all mission to prevent and cure cancer. We would like to thank the Falk Foundation for the generous support and for the chance to organize such an extraordinary and important meeting in Munich. We are convinced that this International Falk Symposium 2012 will lead to a fruitful discussion about colorectal cancer and we would like to invite you all to participate and to benefit from our meeting in Munich. Welcome to Munich! Helmut Friess, Munich Roland M. Schmid, Munich Michael Fried, Zurich Cornelis van de Velde, Leiden 4

Falk Symposium 182 Carcinogenesis, Prevention and Treatment of Colorectal Cancer State of the Art 2012 The Westin Grand Hotel Munich, Registration: Thursday, February 9, 2012 8.00 18.10 h at the congress office Jointly co-organized with the ICRCC Scientific Organization: H. Friess, Munich () R. M. Schmid, Munich () M. Fried, Zurich (Switzerland) C. J. H. van de Velde, Leiden (The Netherlands) Congress Secretary: R. Rosenberg, Munich () S. von Delius, Munich () Congress Venue: The Westin Grand Hotel Arabellastr. 6 81925 Munich Information: Prof. Dr. Helmut Friess Department of Surgery Klinikum rechts der Isar Technische Universität München Ismaninger Str. 22 81675 München Telephone: +49(0)89/4140 21 21 Telefax: +49(0)89/4140 48 70 E-mail: colon2012@chir.med.tu-muenchen.de Official Language: English Call for posters: For details see page 10 Publication date of final program: February 2012 The final program will be available on the homepage www.falkfoundation.org one week before. 5

Friday, February 10, 2012 8.30 Opening remarks H. Friess, R. M. Schmid, Munich Session I Histopathological work-up, carcinogenesis and tumor dissemination Chair: H. Höfler, Munich; A. Perren, Berne 8.40 State-of-the-Art Lecture Histopathological work-up of biopsies, local excisions P. Quirke, and resection specimens in colorectal cancer Leeds 9.05 Molecular pathological pathways in the development T. Kirchner, of colorectal cancer Munich 9.30 Mechanism of colorectal cancer dissemination in C. A. Klein, lymph nodes and distant organs Regensburg 9.55 MicroRNAs and inflammatory cytokines predict diagnosis, C. C. Harris, prognosis and therapeutic outcome of colon cancer Bethesda 10.20 Coffee break with poster session Session II From bench to bed Molecular markers for clinical use Chair: F. R. Greten, Munich; K.-P. Janssen, Munich 10.50 Molecular, blood and stool tests T. F. Imperiale, Ready to replace colonoscopy? Indianapolis 11.15 Genetic and epigenetic mutations and targeted S. Tejpar, therapies in colon cancer Have we made progress? Leuven 11.40 Towards personalization in colon cancer D. J. Kerr, The impact of gene signatures and MSI status Oxford 12.10 Lunch break with poster session 6

Friday, February 10, 2012 Session III Screening- and surveillance programs in low/high risk patients Chair: M. Fried, Zurich; B. Göke, Munich 13.10 Colorectal cancer screening Practice guidelines D. A. Lieberman, Portland 13.35 Hereditary colorectal cancer: Identification, surveillance R. W. Burt, and therapy strategies Salt Lake City 14.00 Inflammatory bowel disease: Cancer risk, detection S. H. Itzkowitz, and surveillance New York 14.25 Chemoprevention of colorectal cancer with 5-ASA H. Herfarth, Chapel Hill 14.50 Coffee break with poster session Session IV Screening modalities, endoscopic adenoma detection and therapy Chair: M. F. Neurath, Erlangen; R. M. Schmid, Munich 15.20 CT- and MR-colonography Challenge for endoscopy? D. C. Rockey, Dallas 15.45 Endoscopic detection of colorectal adenomas: M. Anders, Standards and sophisticated methods T. Rösch, Hamburg 16.10 Endoscopic mucosectomy B. Saunders, London 7

Friday, February 10, 2012 Session V Video session State-of-the-Art colorectal and liver procedures Chair: H. Friess, Munich; M. Ghadimi, Göttingen; E. Tiret, Paris 16.35 Total mesocolic resection in right- and left sided K. Weber, colon cancer W. Hohenberger, Erlangen 17.00 Laparoscopic resection for lower rectal cancer E. Rullier, Bordeaux 17.25 The Holm abdominoperineal resection G. Jansson-Palmer, T. Holm, Stockholm 17.50 Techniques of major hepatic resection for metastatic P. A. Clavien, colorectal cancer Zurich 18.15 End of afternoon session 8

Saturday, February 11, 2012 Session VI Polypectomy and tailored surgery Chair: M. Classen, Reith; C. A. Maurer, Liestal; H. Neuhaus, Düsseldorf 8.30 The difficult polyp Pitfalls for endoscopic removal M. Jung, Mainz 8.55 Endoscopic therapy options for T1 colon and rectal cancer A. Meining, Munich 9.20 Combined endoscopic-laparoscopic resections D. Hahnloser, Zurich 9.55 The TEM procedure Standards and extended indications A. Kartheuser, Brussels 10.20 Coffee break with poster session Session VII Management of non-metastatic colorectal cancer (stage I-III) Chair: H. J. Buhr, Berlin; K.-W. Jauch, Munich; K.-H. Link, Wiesbaden 10.50 Colorectal surgery What is evidence-based and E. Tiret, how should we do it? Paris 11.15 Bowel obstruction in stenotic colorectal cancer P. B. Paty, Stent, stoma or primary resection New York 11.40 Sphincter-saving surgery and reconstruction techniques A. D Hoore, What is reasonable in the context of cure and functional Leuven results? 12.05 Multivisceral resection for T4 or recurrent colorectal R. Tollenaar, cancer? Leiden 12.30 Standards and perspective of adjuvant therapy in W. Schmiegel, colorectal cancer Bochum 12.55 Lunch break with poster session 9

Saturday, February 11, 2012 Session VIII Multimodal therapy in stage II / III rectal cancer Chair: M. Molls, Munich; C. J. H. van de Velde, Leiden; S. D. Wexner, Weston 14.00 Neoadjuvant short- or long-term radio-(chemo)therapy: C. Rödel, How and who should be treated? Frankfurt 14.25 Specimen evaluation and histopathologic prognosticators M. Berho, after neoadjuvant therapy in rectal cancer Weston 14.45 Complete response after neoadjuvant therapy in S. D. Wexner, rectal cancer: To operate or not to operate? Weston 15.05 Which patient does not need a preoperative radiation? M. Büchler, Heidelberg 15.30 Comparison of the Multi-Center trials C. J. H. van de Velde, What could and what did we learn? Leiden 15.55 Presentation of poster prizes Chair: B. Bashankaev, Moscow; D. Kandioler, Vienna; A. Nissan, Jerusalem 16.10 Coffee break with poster session Session IX Management of patients with stage IV colorectal cancer Chair: C.-T. Germer, Würzburg; W. Schmiegel, Bochum; A. Tuchmann, Vienna 16.40 Synchronous resectable liver metastases B. Nordlinger, Technique, results and limitations? Boulogne 17.05 Oncological management of irresectable liver metastases E. van Cutsem, Leuven 17.30 Surgical results after downstaging of initially marginal J. Belghiti, or non-resectable liver metastases? Paris 17.55 Hyperthermic intraperitoneal chemoperfusion in R. Salazar, peritoneal carcinomatosis Barcelona 18.20 End of meeting 10

Poster Session Posters will be exhibited on February 10-11, 2012, at the Westin Grand Hotel in Munich. The authors will be in attendance during coffee and lunch breaks on both days. Poster Jury B. Bashankaev, Moscow; A. Bembenek, Hannover; D. Kandioler, Vienna; M. E. Kreis, Munich; A. Nissan, Jerusalem; C. T. Viehl, Basel Call for posters Please submit your poster abstract before October 15, 2011. Only one-page abstracts not exceeding 250 words, written in English and saved in Microsoft Word format will be accepted. Abstracts must be submitted via our Internet Abstract Submission System (http://www.falkfoundation.com/poster) where further information regarding the submission format and the submission process is available. The abstracts will be selected by the scientific organizers, preference being given to those thematically related to one of the sessions of the program. The accepted abstracts will be printed and distributed to the participants of the congress together with the documents of the meeting. The authors will receive notification about acceptance and further instructions in October 2011. Contact address for further information on the poster session: Falk Foundation e.v. P.O. Box 6529 79041 Freiburg/ Telephone: +49 (0) 761 / 15 14-0 Telefax: +49 (0) 761 / 15 14-359 Web address for submitting poster abstracts: http://www.falkfoundation.com/poster For the first author of an accepted poster, expenses for accommodation (February 9 12, 2012) and fees for the scientific program and evening activities will be covered during the Falk Symposium 182. Travel expenses are not covered. Poster prizes Three prizes will be awarded for the best presentations. Prize winners will be presented with a prize certificate and 1.500,-, 1.000,- and 500,- respectively. Travel expenses will be covered additionally for the first author of prize winning posters. 11

List of Speakers, Moderators and Scientific Organizers PD Dr. Mario Anders Klinik und Poliklinik für Interdisziplinäre Endoskopie Universitätsklinikum Eppendorf Martinistr. 52 20251 Hamburg m.anders@uke.uni-hamburg.de Dr. Badma Bashankaev National Research Center of Surgery Department of Colorectal and Pelvic Floor Surgery 2 Abrikosovsky per. 119992 Moskau Russia badma.bashankaev@gmail.com Prof. Dr. Jacques Belghiti Hôpital Beaujon Department of Surgery 100, Bd. Général Leclerc 92118 Clichy France jacques.belghiti@bjn.ap-hop-paris.fr PD Dr. Andreas Bembenek Klinik für Viszeralchirurgie Krankenhaus Siloah Klinikum Region Hannover Roesebeckstr. 15 30449 Hannover andreas.bembenek@krh.eu Mariana Berho, M.D. Professor of Medicine Cleveland Clinic Florida Department of Pathology 2950 Cleveland Clinic Boulevard Weston FL 33331 USA berhom@ccf.org 12 Prof.Dr.Dr.h.c.mult. Markus Büchler Abteilung für Allgemeine, Viszerale und Transplantationschirurgie Universitätsklinikum Heidelberg Im Neuenheimer Feld 110 69120 Heidelberg markus.buechler@med.uni-heidelberg.de Prof. Dr. Heinz J. Buhr Allgemein-,Gefäß- und Thoraxchirurgie Charité Universitätsmedizin Campus Benjamin Franklin (CBF) Hindenburgdamm 30 12203 Berlin heinz.buhr@charite.de Randall W. Burt, M.D. Professor of Medicine University of Utah Huntsman Cancer Institute 2000 Circle of Hope Salt Lake City UT 84112 USA randall.burt@hci.utah.edu Prof.Dr.Dr.h.c.mult. Meinhard Classen Golfweg 11 6370 Reith b. Kitzbühel Austria Prof. Dr. Pierre-Alain Clavien Universitätsspital Zürich Klinik für Viszeral- und Transplantationschirurgie Rämistrasse 100 8091 Zürich Switzerland pierre-alain.clavien@usz.ch PD Dr. Stefan von Delius II. Medizinische Klinik und Poliklinik Klinikum rechts der Isar der Technischen Universität Ismaninger Str. 22 81675 München stefan.von-delius@lrz.tum.de

Prof. Dr. André D Hoore Department of Abdominal Surgery University Clinics Gasthuisberg Herestraat 49 3000 Leuven Belgium andre.dhoore@uz.kuleuven.ac.be Prof. Dr. Michael Fried Universitätsspital Zürich Klinik für Gastroenterologie und Hepatologie Rämistrasse 100 8091 Zürich Switzerland michael.fried@usz.ch Prof. Dr. Helmut Friess Chirurgische Klinik und Poliklinik Klinikum rechts der Isar der Technischen Universität Ismaninger Str. 22 81675 München helmut.friess@chir.med.tu-muenchen.de Prof. Dr. Michael Ghadimi Abteilung für Allgemein- und Viszeralchirurgie Universitätskliniken Göttingen Robert-Koch-Str. 40 37075 Göttingen mghadim@uni-goettingen.de Prof. Dr. Christoph-Thomas Germer Klinik und Poliklinik für Allgemein- und Viszeralchirurgie Klinikum der Universität Würzburg Oberdürrbacher Str. 6 97080 Würzburg germer_c@chirurgie.uni-wuerzburg.de Prof. Dr. Burkhard Göke Medizinische Klinik und Poliklinik II Klinikum der Universität München - Großhadern Marchioninistr. 15 81377 München burkhard.goeke@med.uni-muenchen.de Prof. Dr. Florian R. Greten II. Medizinische Klinik und Poliklinik Klinikum rechts der Isar der Technischen Universität Ismaninger Str. 22 81675 München florian.greten@lrz.tum.de PD Dr. Dieter Hahnloser Universitätsspital Zürich Klinik für Viszeral- und Transplantationschirurgie Rämistrasse 100 8091 Zürich Switzerland dieter.hahnloser@usz.ch Curtis C. Harris, M.D. Professor of Medicine National Cancer Institute Center for Cancer Research Laboratory of Human Carcinogenesis 31 Center Drive Bethesda MD 20892 USA curtis_harris@nih.gov Hans Herfarth, M.D. Associate Professor of Medicine University of North Carolina Gastroenterology & Hepatology 4151 Bioinformatics Bldg. 130 Mason Farm Road Chapel Hill NC 27599-7080 USA hherf@med.unc.edu Prof. Dr. Heinz Höfler Institut für Allgemeine Pathologie und Pathologische Anatomie Klinikum rechts der Isar der Technischen Universität Ismaninger Str. 22 81675 München hoefler@lrz.tu-muenchen.de 13

Prof. Dr.Dr.h.c. Werner Hohenberger Chirurgische Klinik und Poliklinik Universitätsklinikum Erlangen Krankenhausstr. 12 91054 Erlangen werner.hohenberger@uk-erlangen.de Prof. Dr. Torbjorn Holm Department of Colorectal Surgery Karolinska University Hospital Solna I171 76 Stockholm Sweden holm@karolinska.se Thomas F. Imperiale, M.D. Professor of Medicine Indiana University Division of Gastroenterology 1050 Wishard Blvd. Indianapolis IN 46202 USA timperia@iupui.edu Steven H. Itzkowitz, M.D. Professor of Medicine Mount Sinai School of Medicine Division of Gastroenterology Box 1069 One Gustave L. Levy Place New York NY 10029-6574 USA steven.itzkowitz@mountsinai.org PD Dr. Klaus-Peter Janssen Chirurgische Klinik und Poliklinik Klinikum rechts der Isar der Technischen Universität Ismaninger Str. 22 81675 München klaus-peter.janssen@lrz.tum.de Dr. Gabriella Jansson-Palmer Department of Colorectal Surgery Karolinska University Hospital Solma 171 76 Stockholm Sweden gabriella-jansson-palmer@karolinska.se 14 Prof. Dr. Karl-Walter Jauch Chirurgische Klinik und Poliklinik Klinikum der Universität München - Großhadern Marchioninistr. 15 81377 München karl-walter.jauch@med.uni-muenchen.de Prof. Dr. Michael Jung Klinik für Innere Medizin Katholisches Klinikum Mainz St. Hildegardis-Krankenhaus Hildegardstr. 2 55131 Mainz m.jung.hildegardis-mz@t-online.de Prof. Dr. Daniela Kandioler Klinik für Chirurgie Medizinische Universität Wien Leitstelle 21A Währinger Gürtel 18-20 1090 Wien Austria daniela.kandioler@meduniwien.ac.at Prof. Dr. Alex Kartheuser Clinique Universitaire St. Luc Service de Chirurgie de l Appareil Digestif Avenue Hippocrate 10 1200 Bruxelles Belgium kartheuser@chir.ucl.ac.be Prof. Dr. David J. Kerr University of Oxford Department of Clinical Phramacology Old Road Campus off Roosevelt Dr Oxford OX3 7DQ Great Britain david.kerr@clinpharm.ox.ac.uk

Prof. Dr. Thomas Kirchner Pathologisches Institut LMU München Thalkirchner Str. 36 80337 München thomas.kirchner@med.uni-muenchen.de Prof. Dr. Christoph A. Klein Institut für Pathologie Universitätsklinikum Regensburg 93042 Regensburg christoph.klein@klinik.uni-regensburg.de Prof. Dr. Martin E. Kreis Chirurgische Klinik und Poliklinik Klinikum der Universität München - Großhadern Marchioninistr. 15 81377 München martin.kreis@med.uni-muenchen.de David A. Lieberman, M.D. Professor of Medicine Oregon Health & Science Univ. Division of Gastroenterology L461 3181 SW Sam Jackson Park Road Portland OR 97239 USA lieberma@ohsu.edu Prof. Dr. Karl-H. Link Chirurgisches Zentrum Asklepios Paulinen Klinik Geisenheimer Str. 10 65197 Wiesbaden k-h.link@asklepios.com Prof. Dr. Christoph A. Maurer Kantonsspital Liestal Chirurgische Klinik Rheinstr. 26 4410 Liestal Switzerland christoph.maurer@ksli.ch Prof. Dr. Alexander Meining II. Medizinische Klinik und Poliklinik Klinikum rechts der Isar der Technischen Universität Ismaninger Str. 22 81675 München alexander.meining@irz.tum.de Prof. Dr. Michael Molls Klinik und Poliklinik für Strahlentherapie Klinikum rechts der Isar der Technischen Universität Ismaninger Str. 22 81675 München molls@lrz.tum.de Prof. Dr. Horst Neuhaus Innere Medizin Evangelisches Krankenhaus Kirchfeldstr. 40 40217 Düsseldorf horst.neuhaus@evk-duesseldorf.de Prof. Dr. Markus F. Neurath Medizinische Klinik I Universitätsklinikum Erlangen Ulmenweg 18 91054 Erlangen markus.neurath@uk-erlangen.de Prof. Dr. Aviram Nissan Hadassah University Hospital Mt. Scopus Deoartment of Surgery P. O. Box 24035 91240 Jerusalem Israel anissan@hadassah.org.il Prof. Dr. Bernard Nordlinger Hôpital Ambroise Paré Department of Digestive Surgery 92104 Boulogne France bernard.nordlinger@apr.aphp.fr 15

Philip B. Paty, M.D. Memorial Sloan-Kettering Cancer Center Department of Surgery Colorectal Service 1275 York Avenue New York NY 10065 USA patyp@mskcc.org Prof. Dr. Aurel Perren Universität Bern Pathologisches Institut Murtenstraße 31 3010 Bern Switzerland aurel.perren@pathology.unibe.ch Prof. Dr. Phil Quirke St. James s University Hospital Pathology and Tumour Biology Wellcome Trust Brenner Bldg. Beckett Street Leeds LS9 7TF Great Britain p.quirke@leeds.ac.uk Don C. Rockey, M.D. Professor of Medicine University of Texas Southwestern Medical Center Div. of Digestive & Liver Diseas 5959 Harry Hines Boulevard Dallas TX 75390 USA don.rockey@utsouthwestern.edu Prof. Dr. Claus Rödel Klinik für Strahlentherapie und Onkologie Klinikum der Johann Wolfgang Goethe-Universität Frankfurt Theodor-Stern-Kai 7 60596 Frankfurt claus.roedel@kgu.de Prof. Dr. Thomas Rösch Klinik und Poliklinik für Interdisziplinäre Endoskopie Universitätsklinikum Eppendorf Martinistr. 52 20251 Hamburg t.roesch@uke.de PD Dr. Robert Rosenberg Chirurgische Klinik und Poliklinik Klinikum rechts der Isar der Technischen Universität Ismaninger Str. 22 81675 München rosenberg@chir.med.tu-muenchen.de Prof. Dr. Eric Rullier Hôpital Universitaire Saint André Department of Surgery 1 Rue Jeau Burguel 33075 Bordeaux Cedex France eric.rullier@chu-bordeaux.fr Prof. Dr. Ramon Salazar Institut Catalá d Oncologia IDIBELL Gran Via s/n, Km 2.7 08907 L Hospitalet, Barcelona Spain ramonsalazar@iconcologia.net Dr. Brian Saunders St. Mark s Hospital Wolfson Unit for Endoscopy Watford Road Harrow HA1 3UJ Great Britain b.saunders@imperial.ac.uk Prof. Dr. Roland M. Schmid II. Medizinische Klinik und Poliklinik Klinikum rechts der Isar der Technischen Universität Ismaninger Str. 22 81675 München roland.schmid@lrz.tum.de 16

Prof. Dr. Wolff Schmiegel Medizinische Universitätsklinik Ruhr-Universität Bochum In der Schornau 23-25 44892 Bochum wolff.schmiegel@ruhr-uni-bochum.de Prof. Dr. Sabine Tejpar Digestive Oncology Unit University Ziekenhuis Gasthuisberg Herestraat 49 3000 Leuven Belgium sabine.tejpar@uz.kuleuven.ac.be Prof. Dr. Emmanuel Tiret Hôpital Saint Antoine Service de Chirurgie Digestive 184, Rue du Faubourg St.-Antoine 75571 Paris France emmanuel.tiret@sat.aphp.fr Prof. Dr. R. Tollenaar Leiden University Medical Center Department of Surgery PO Box 9600 2300 RC Leiden The Netherlands r.a.e.m.tollenaar@lumc.nl Prof. Dr. Albert Tuchmann Krankenhaus Florisdorf I. Chirurgische Abteilung Hinaysgasse 1 1210 Wien Austria albert.tuchmann@wienkav.at Prof. Dr. Eric van Cutsem Division of Digestive Oncology University of Leuven Herestraat 49 3000 Leuven Belgium eric.vancutsem@med.kuleuven.be Prof. Dr. C. J. H. van de Velde Department of Surgery Leiden University Medical Center P. O. Box 9600 2300 RC Leiden The Netherlands c.j.h.van_de_velde@lumc.nl PD Dr. Carsten T. Viehl Universitätsspital Basel Viszeralchirurgie Spitalgasse 21 4031 Basel Switzerland cviehl@uhbs.ch Dr. Klaus Weber Chirurgische Klinik und Poliklinik Universitätsklinikum Erlangen-Nürnberg Krankenhausstr. 12 91054 Erlangen klaus.weber@uk-erlangen.de Steven D. Wexner, M.D. Professor of Medicine Cleveland Clinic Florida Department of Colorectal Surgery 2950 Cleveland Clinic Boulevard Weston FL 33331 USA wexners@ccf.org 17

General Information Prior to the opening of the congress in Munich Falk Foundation e. V. Telephone: +49 (0) 761 / 15 14-0 Congress Division Telefax: +49 (0) 761 / 15 14-359 Leinenweberstr. 5 E-mail: symposia@falkfoundation.de P.O. Box 6529 79041 Freiburg/Br. () Congress Office During the V Falk Gastro-Conference The Westin Grand Hotel Telephone: +49 (0) 171/7 84 61 15 Arabellastr. 6 Telefax: +49 (0) 89 / 92 64 92 01 81925 Munich Opening Hours: Tuesday, February 7, 2012 Wednesday, February 8, 2012 Thursday, February 9, 2012 Friday, February 10, 2012 Saturday, February 11, 2012 16.00 21.00 h 7.30 18.00 h 8.00 18.10 h 8.00 18.15 h 8.00 18.10 h Congress Fees Scientific program of the Falk Symposium 182 200,- Students and residents 100,- * * * OR * * * Day ticket 120,- Students and residents 60,- The congress fees include: - Welcome Evening on February 7, 2012 - Refreshments during coffee breaks - Lunch on February 10 and 11, 2012 - A copy of the abstract volume 18

Registration Congress registrations must reach the Falk Foundation e.v. by November 30, 2011 at the latest. Congress fees may be paid by cheque payable to the Falk Foundation e.v. or by bank transfer to Volksbank Freiburg e.g.,, Bank No. 68090000, Account No. 1452010, IBAN DE33 6809 0000 0001 4520 10, BIC Genode 61 FR1. Please mark bank transfers with V Falk Gastro-Conference. To ensure correct registration, participants are asked to send in their registration and the fee remittance together. After receipt of registration form, each participant will be provided with confirmation of his registration. On presentation of this confirmation at the Congress Office in Munich participants will receive the congress folder containing name badges, admission tickets and the abstract volume. In the event of registration cancellations, a handling fee of EUR 20,- will be deducted from the refund. All participants will receive a written confirmation of attendance at the end of the meeting. Admission to Scientific Events For admission to scientific events your name badge should be clearly visible. Hotel Accommodation Hotel reservations can be made online: www.booking.com/hotels 19

Congress Report The official congress report of the Falk Symposium 182 Carcinogenesis, Prevention and Treatment of Colorectal Cancer State-of-the-Art 2012 will be published in English in the second half of 2012 by Karger Publishers, Basel, Switzerland. Orders for this book at a reduced subscription price of 35,- can be placed at the Congress Office during the congress in Munich. Congress Short Report The congress short report of the V Falk Gastro-Conference will be published by the Falk Foundation e.v. with number FSK 181-182 in the second half on 2012. Orders for this short report, free of charge, can be placed with the Falk Foundation e.v. Airport International Airport Munich 20

General Information: FALK FOUNDATION e.v. Leinenweberstr. 5 79108 Freiburg Congress Division Telephone: +49(0)761/1514-0 Telefax: +49(0)761/1514-359 E-mail: symposia@falkfoundation.de www.falkfoundation.org VP 182 1-4/2011/5.000 Stü