Chefarzt Alterspsychiatrie, Clienia Privatklinik Schlössli, Oetwil am See

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1 Priv.-Doz. Dr. med. Thomas Zetzsche geboren in Stuttgart Berufliche Ausbildung und Tätigkeit Studium der Humanmedizin an der Philipps-Universität, Marburg/Lahn Studium Fortführung an der Georg-August-Universität, Göttingen 1986 Praktisches Jahr, Wahlfach Neurologie an der Neurologischen Klinik, Georg-August-Universität, Göttingen Assistenzarzt an der Neurologischen Klinik, Georg-August-Universität, Göttingen 1988 Promotion am Institut für klinische Neuroanatomie und Entwicklungsneurobiologie der Georg-August-Universität, Göttingen Arzt und wissenschaftlicher Mitarbeiter an der Neurologischen Klinik und Poliklinik, Universitätsspital Zürich Arzt und wissenschaftlicher Mitarbeiter am Max-Planck-Institut für Psychiatrie (Deutsche Forschungsanstalt für Psychiatrie), München Psychotherapie Ausbildung (Verhaltenstherapie und Zweitverfahren Tiefenpsychologie) am Max-Planck-Institut für Psychiatrie, München und am Centrum für Integrative Psychotherapie (CIP), München Arzt und wissenschaftlicher Mitarbeiter an der Klinik und Poliklinik für Psychiatrie und Psychotherapie, Ludwig-Maximilians-Universität (LMU), München ab 2006 Oberarzt für die Privatstationen und die Privatambulanz der Klinik, 2009 Habilitation und Venia legendi für das Fach Psychiatrie und Psychotherapie, Privatdozent an der LMU, München seit Chefarzt Alterspsychiatrie, Clienia Privatklinik Schlössli, Oetwil am See Publikationen Originalartikel: 1) Wolff JR, Böttcher H, Zetzsche T, Oertel WH, Chronwall BM (1984). Development of GABAergic neurons in rat visual cortex as identified by glutamate decarboxylase-like immunoreactivity. Neuroscience Letters 47 (3): (IF: 2.09) 2) Wolff JR, Balcar VJ, Zetzsche T, Böttcher H, Schmechel DE, Chronwall BM (1984). Development of GABA-ergic system in rat visual cortex. Advances in Experimental Medicine and Biology 181: (IF: 0.65) 3) Zetzsche T, Baimbridge KG, Möhler H, Chan-Palay V (1990). Subsets of GABA neurons in the human cerebellum in normal controls and senile dementia of the Alzheimer type patients detected by glutamate decarboxylase, GABAA /benzodiazepine receptor protein, calbindin D-28k and parvalbumin immunocytochemistry.

2 Dementia and Geriatric Cognitive Disorders 1: (IF: 2.51) 4) Höchli M, Zetzsche T, Chan-Palay V (1991). Parvalbumin-immunoreactive neurons in the normal human hippocampus. Dementia and Geriatric Cognitive Disorders 2: (IF: IF: 2.51) 5) Chan-Palay V, Zetzsche T, Höchli M (1991). Parvalbumin neurons in the hippocampus in senile dementia of the Alzheimer type, Parkinson s disease and multi infarct dementia. Dementia and Geriatric Cognitive Disorders 2: (IF: IF: 2.51) 6) Zetzsche T, Chan-Palay V (1992). MAO A and B immunoreactivity in the hippocampus, temporal cortex and cerebellum of normal controls and of patients with senile dementia of the Alzheimer type. Dementia and Geriatric Cognitive Disorders 3: (IF: IF: 2.51) 7) Chan-Palay V, Höchli M, Jentsch B, Leonard B, Zetzsche T (1992). Raphe serotonin neurons in the human brain stem in normal controls and patients with senile dementia of the Alzheimer type and Parkinson s disease: relationship to monoamine oxidase enzyme localization. Dementia and Geriatric Cognitive Disorders 3: (IF: IF: 2.51) 8) Balcar VJ, Zetzsche T, Wolff JR (1992). Glutamate decarboxylase in developing rat neocortex: Does it correlate with the differentiation of GABAergic neurons and synapses? Neurochemical Research 17 (3): (IF: 2.14) 9) Frasch A, Zetzsche T, Steiger A, Jirikowski GF (1995). Reduction of plasma oxytocin levels in patients suffering from major depression. Advances in Experimental Medicine and Biology 395: (IF: 0.65) 10) Probst JC, Zetzsche T, Weber M, Theilemann P, Skutella T, Landgraf R, Jirikowski GF (1996). Human intestinal trefoil factor is expressed in human hypothalamus and pituitary: evidence for a novel neuropeptide. Journal of the Federation of American Societies for Experimental Biology (FASEB J) 10 (13): (IF: 6.72) 11) Soyka M, Zetzsche T, Dresel S, Tatsch K (2000). FDG-PET and IBZM-SPECT suggest reduced thalamic activity but no dopaminergic dysfunction in chronic alcohol hallucinosis. Journal of Neuropsychiatry and Clinical Neuroscience 12 (2): (IF: 2.14) 12) Meisenzahl EM, Frodl T, Zetzsche T, Leinsinger G, Heiss D, Maag K, Hegerl U, Hahn K, Möller H- J (2000). Adhesio interthalamica in male patients with schizophrenia. American Journal of Psychiatry 157 (5): (IF: 6.58) 13) Zetzsche T, Meisenzahl EM, Preuss UW, Holder JJ, Kathmann N, Leinsinger G, Hahn K, Hegerl U, Möller H-J (2001). In-vivo analysis of the human planum temporale (PT): Does the definition of PT borders influence the results with regard to cerebral asymmetry and correlation with handedness? Psychiatry Research: Neuroimaging 107 (2): (IF: 2.35)

3 14) Frodl T, Meisenzahl E, Zetzsche T, Bottlender R, Born C, Groll C, Jäger M, Leinsinger G, Hahn K, Möller H-J (2002). Enlargement of the amygdala in patients with a first episode of major depression. Biological Psychiatry 51 (9): (IF: 5.91) 15) Frodl T, Meisenzahl EM, Zetzsche T, Born C, Groll C, Jäger M, Leinsinger G, Bottlender R, Hahn K, Möller H-J (2002). Hippocampal changes in patients with a first episode of major depression. American Journal of Psychiatry 159 (7): (IF: 6.46) 16) Meisenzahl EM, Zetzsche T, Preuss U, Frodl T, Leinsinger G, Möller H-J (2002). Does the definition of borders of the planum temporale influence the results in schizophrenia? American Journal of Psychiatry 159 (7): (IF: 6.46) 17) Meisenzahl EM, Frodl T, Zetzsche T, Leinsinger G, Maag K, Hegerl U, Hahn K, Möller H-J (2002). Investigation of a possible diencephalic pathology in schizophrenia. Psychiatry Research: Neuroimaging 115 (3): (IF: 2.23) 18) Preuss UW, Meisenzahl EM, Frodl T, Zetzsche T, Holder J, Leinsinger G, Hegerl U, Hahn K, Möller H-J (2002). Handedness and corpus callosum morphology. Psychiatry Research: Neuroimaging 116 (1-2): (IF: 2.23) 19) Frodl T, Meisenzahl EM, Zetzsche T, Born C, Jäger M, Groll C, Bottlender R, Leinsinger G, Möller H-J (2003). Larger amygdala volumes in first depressive episode as compared to recurrent major depression and healthy control subjects. Biological Psychiatry 53 (4): (IF: 6.04) 20) Frodl T, Meisenzahl EM, Zetzsche T, Höhne T, Banac S, Schorr C, Jäger M, Leinsinger G, Bottlender R, Reiser M, Möller H-J (2004). Hippocampal and amygdala changes in patients with major depressive disorder and healthy controls during a 1-year follow-up. Journal of Clinical Psychiatry 65 (4): (IF: 4.81) 21) Meisenzahl EM, Frodl T, Müller D, Schmitt G, Gallinat J, Zetzsche T, Marcuse A, Juckel G, Leinsinger G, Hahn K, Möller H-J, Hegerl U (2004). Superior temporal gyrus and P300 in schizophrenia: A combined ERP/structural magnetic resonance imaging investigation. Journal of Psychiatric Research 38 (2): (IF: 3.08) 22) Preuss UW, Zetzsche T, Jäger M, Groll C, Frodl T, Bottlender R, Leinsinger G, Hegerl U, Hahn K, Möller H-J, Meisenzahl EM (2005). Thalamic volume in first-episode and chronic schizophrenic subjects: A volumetric MRI study. Schizophrenia Research 73 (1): (IF: 4.23) 23) Meisenzahl EM, Scheuerecker J, Zipse M, Ufer S, Wiesmann M, Frodl T, Koutsouleris N, Zetzsche T, Schmitt G, Riedel M, Spellmann I, Dehning S, Linn J, Bruckmann H, Möller H-J (2006). Effects of treatment with the atypical neuroleptic quetiapine on working memory function: A functional MRI follow-up investigation. European Archives of Psychiatry and Clinical Neuroscience 256 (8): (IF: 3.04)

4 24) Frodl T, Schaub A, Banac S, Charypar M, Jäger M, Kümmler P, Bottlender R, Zetzsche T, Born C, Leinsinger G, Reiser M, Möller H-J, Meisenzahl EM (2006). Reduced hippocampal volume correlates with executive dysfunctioning in major depression. Journal of Psychiatry and Neuroscience 31 (5): (IF: 4.10) 25) Zetzsche T, Frodl T, Preuss UW, Schmitt G, Seifert D, Leinsinger G, Born C, Reiser M, Möller H-J, Meisenzahl EM (2006). Amygdala volume and depressive symptoms in patients with borderline personality disorder. Biological Psychiatry 53 (4): (IF: 7.15) 26) Rujescu D, Meisenzahl EM, Krejcova S, Giegling I, Zetzsche T, Reiser M, Born CM, Möller H-J, Veske A, Gal A, Finckh U (2007). Plexin B3 is genetically associated with verbal performance and white matter volume in human brain. Molecular Psychiatry 12 (2): (IF: 11.80) 27) Zetzsche T, Preuss UW, Frodl T, Schmitt G, Seifert D, Münchhausen E, Tabrizi S, Leinsinger G, Born C, Reiser M, Möller H-J, Meisenzahl EM (2007). Hippocampal volume reduction and history of aggressive behaviour in patients with borderline personality disorder. Psychiatry Research: Neuroimaging 154 (2): (IF: 2.75) 28) Zetzsche T, Preuss UW, Frodl T, Watz D, Schmitt G, Koutsouleris N, Born C, Reiser M, Möller H- J., Meisenzahl EM (2007). In-vivo topography of structural alterations of the anterior cingulate in patients with schizophrenia: New findings and comparison with the literature. Schizophrenia Research 96 (1-3): (IF: 4.26) 29) Scheuerecker J, Frodl T, Koutsouleris N, Zetzsche T, Wiesmann M, Kleemann AM, Brückmann H, Schmitt G, Möller H-J, Meisenzahl EM (2007). Cerebral differences in explicit and implicit emotional processing - an fmri study. Neuropsychobiology 56 (1): (IF: 2.37) 30) Zetzsche T, Preuss U, Bondy B, Frodl T, Zill P, Schmitt G, Koutsouleris N, Rujescu D, Born C, Reiser M, Möller H-J, Meisenzahl EM (2008). Association between 5-HT1A receptor gene C-1019 G polymorphism and amygdala volume in patients with borderline personality disorder. Genes, Brain and Behavior 7: (IF: 4.38) 31) Scheuerecker J, Ufer S, Zipse M, Frodl T, Koutsouleris N, Zetzsche T, Wiesmann M, Albrecht J, Brückmann H, Schmitt G, Möller H-J, Meisenzahl EM (2008). Cerebral changes and cognitive dysfunctions in medication-free schizophrenia - an fmri study. Journal of Psychiatric Research 42 (6): (IF: 3.70) 32) Preuss UW, Rujescu D, Giegling I, Watzke S, Koller G, Zetzsche T, Meisenzahl EM, Soyka M, Möller H-J (2008). Psychometrische Evaluation der deutschsprachigen Version der Barratt- Impulsiveness-Skala. Der Nervenarzt 79 (3): (IF: 0.71) 33) Koutsouleris N, Gaser C, Jäger M, Bottlender R, Frodl T, Holzinger S, Schmitt G, Zetzsche T, Burgermeister B, Scheuerecker J, Born C, Reiser M, Möller H-J, Meisenzahl EM (2008). Structural

5 correlates of psychopathological symptom dimensions in schizophrenia: A voxel-based morphometric study. Neuroimage 39 (4): (IF: 5.56) 34) Frodl T, Jäger M, Born C, Ritter S, Kraft E, Zetzsche T, Bottlender R, Leinsinger G, Reiser M, Möller H-J, Meisenzahl E (2008). Anterior cingulate cortex does not differ between patients with major depression and healthy controls, but relatively large anterior cingulate cortex predicts a good clinical course. Psychiatry Research: Neuroimaging 163: (IF: 2.75) 35) Zetzsche T, Preuss U, Bondy B, Frodl T, Zill P, Schmitt G, Koutsouleris N, Rujescu D, Born C, Reiser M, Möller H-J, Meisenzahl EM (2008). White matter alterations in schizophrenic patients with pronounced negative symptomatology and with positive family history for schizophrenia. European Archives of Psychiatry and Clinical Neuroscience, 258 (5): (IF: 3.04) 36) Frodl T, Zill P, Baghai T, Schüle C, Rupprecht R, Zetzsche T, Bondy B, Reiser M, Möller H-J, Meisenzahl EM (2008). Reduced hippocampal volumes associated with the long variant of the tri- and diallelic serotonin transporter polymorphism in major depression. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 147B (7): (IF: 4.46) 37) Koutsouleris N, Meisenzahl EM, Davatzikos C, Bottlender R, Frodl T, Scheuerecker J, Schmitt G, Zetzsche T, Decker P, Reiser M, Möller HJ, Gaser C (2009). Use of neuroanatomical pattern classification to identify subjects in at-risk mental states of psychosis and predict disease transition. Archives of General Psychiatry 66 (7): (IF: 10.78) 38) Preuss UW, Zetzsche T, Pogarell O, Mulert C, Frodl T, Müller D, Schmidt G, Born C, Reiser M, Möller HJ, Hegerl U, Meisenzahl EM (2010). Anterior cingulum volumetry, auditory P300 in schizophrenia with negative symptoms. Psychiatry Research: Neuroimaging 183 (2): (IF: 2.06) 39) Zetzsche T, Rujescu D, Hardy J, Hampel H (2010). Advances and perspectives from genetic research: development of biological markers in Alzheimer's disease. Expert Review of Molecular Diagnostics10 (5): (IF: 4.65) 40) Meisenzahl EM, Seifert D, Bottlender R, Teipel S, Zetzsche T, Jäger M, Koutsouleris N, Schmitt G, Scheuerecker J, Burgermeister B, Hampel H, Rupprecht T, Born C, Reiser M, Möller HJ, Frodl T (2010). Differences in hippocampal volume between major depression and schizophrenia: a comparative neuroimaging study. European Archives of Psychiatry and Clinical Neuroscience 260 (2): (IF: 3.04) 41) Juckel G, Mergl R, Brüne M, Villeneuve I, Frodl T, Schmitt G, Zetzsche T, Born C, Hahn K, Reiser M, Möller HJ, Bär KJ, Hegerl U, Meisenzahl EM (2011). Is evaluation of humorous stimuli associated with frontal cortex morphology? A pilot study using facial micro-movement analysis and MRI. Cortex 47 (5): (IF: 7.25) Buchbeiträge und Kongreßproceedings: 1) Zetzsche T, Chan-Palay V (1993). GABA neurons and innervation by tryptophan hydroxylase (PH8) and monoamine oxidase B immunoreactive axons in the human cerebellum. In: Serotonin, the Cerebellum and Ataxia, eds.: Trouillas P, Fuxe K. Raven Press, New York. Pages: ) Chan-Palay V, Höchli M, Jentsch B, Cotton RGH, Zetzsche T (1993). A quantitative study of the raphe serotonin neurons in the normal human brain stem. In: Serotonin, the Cerebellum and Ataxia, eds.: Trouillas P, Fuxe K. Raven Press, New York. Pages:

6 3) Zetzsche T, Skutella T, Jirikowski GF, Probst JC (1995). Localization of hp1.b trefoil peptide in human brain: Evidence for a new neuropeptide. Proceedings of the 23rd Göttingen Neurobiology Conference, Volume II: S863. 4) Zetzsche T, Frodl T, Preuss UW, Seifert D, Möller H-J, Meisenzahl EM (2009). Neurobiology of Borderline Personality Disorder: Present State and Future Directions. In: Borderline Personality Disorder: New Research. Eds.: Jackson MH, Westbrook LF. Nova Science Publishers Inc., New York. Pages: Zitierfähige Kongreßbeiträge / Abstracts: 1) Zetzsche T, Balcar V, Wolff JR (1985). Comparison of GAD in early postnatal and adult cortex. Journal of Neurochemistry 44 (Suppl 1): ) Balcar VJ, Zetzsche T, Wolff JR (1985). Development of GABAergic inhibition in the rat visual cortex. Biological Chemistry Hoppe-Seyler 366 (2): ) Zetzsche T, Frasch A, Jirikowski G, Murck H, Steiger A (1995). Nocturnal plasma concentrations of oxytocin are reduced in patients with depression compared with age-matched controls. Pharmacopsychiatry 28: ) Probst JC, Landgraf R, Stalla GK, Zetzsche T (1996). Differential distribution of trefoil polypeptides in the hypothalamo-hypophyseal system and immune system. Regulatory Peptides 64 (1): ) Zetzsche T, Frasch A, Jirikowski G, Murck H, Steiger A (1996). Nocturnal oxytocin secretion is reduced in major depression. Biological Psychiatry 39 (7): ) Kathmann N, Meisenzahl E, Zetzsche T (1999). Localizing brain regions active in spatial and nonspatial working memory using fmri. Psychophysiology 36: S66 Suppl. 7) Meisenzahl EM, Kathmann N, Zetzsche T, Heiss D, Leinsinger G, Möller H-J (1999). Localizing brain regions active in spatial and nonspatial working memory using fmri. Pharmacopsychiatry 32: ) Zetzsche T, Meisenzahl EM, Holder J, Leinsinger G, Heiss D, Unger J, Hegerl U, Möller H-J (1999). Planum temporale: Loss of asymmetry in schizophrenic patients? Pharmacopsychiatry 32: ) Zetzsche T, Holder J, Leinsinger G, Preuss UW, Hegerl U, Möller H-J, Meisenzahl EM (2000). Possible disturbance of planum temporale (PT) asymmetry in schizophrenia: Does the definition of PT borders influence the results? NeuroImage 11 (5), Suppl. 1: S ) Holder J, Zetzsche T, Leinsinger G, Preuss UW, Hegerl U, Möller H-J, Meisenzahl EM (2000). Asymmetry of the planum temporale and handedness in healthy right-handed males. NeuroImage 11 (5) Suppl. 1: S810.

7 11) Meisenzahl EM, Kathmann N, Heiss DT, Zetzsche T, Hahn K, Leinsinger GL, Möller H-J (2000). Evaluation of working memory in functional MR imaging with different memory tasks. European Neuropsychopharmacology 10, Suppl. 3: ) Kathmann N, Meisenzahl E, Zetzsche T (2001). Localizing brain regions active in spatial and nonspatial working memory using fmri. Journal of Psychophysiology 15 (2): ) Preuss U, Zetzsche T, Möller H-J, Meisenzahl E (2001). MRI volumetry of the thalamus in schizophrenia. The World Journal of Biological Psychiatry 2 (Suppl. 1): 247S. 14) Zetzsche T, Preuss U, Kathmann N, Möller H-J, Meisenzahl E (2001). In-vivo analysis of the human planum temporale: Does the definition of PT borders influence the results with regard to cerebral asymmetry and correlation with handedness. The World Journal of Biological Psychiatry 2 (Suppl. 1): 246S. 15) Meisenzahl EM, Zetzsche T, Preuss U, Holder J, Leinsinger G, Hegerl U, Hahn K, Möller HJ (2001). Planum temporale in schizophrenia: Does the definition of borders influence the results? The World Journal of Biological Psychiatry 2 (Suppl. 1): 246S. 16) Preuss U, Zetzsche T, Münchhausen E, Möller H-J, Meisenzahl E (2002). Morphological brain changes related to impulsive and aggressive behaviour? A structural magnetic resonance imaging study. European Archives of Psychiatry and Clinical Neuroscience 252: ) Schmitt GJ, Frodl T, Zetzsche T, Decker P, Sievers M, Bottlender R, Leinsinger G, Möller H-J, Meisenzahl EM (2003). Hirnstrukturelle Veränderungen bei Patienten mit psychosenaher Symptomatik im Vergleich zu ersterkrankten Patienten mit einer Schizophrenie und gesunden Kontrollprobanden. Nervenarzt 74 (Suppl. 2): S ) Zetzsche T, Preuss UW, Frodl T, Möller H-J, Meisenzahl EM (2003). Possible changes of hippocampus and amygdala in borderline personality disorder: A structural magnetic resonace imaging study. Pharmacopsychiatry 36: ) Frodl T, Zetzsche T, Höhne T, Banac S, Schorr C, Jäger M, Leinsinger G, Bottlender R, Reiser M, Möller H-J, Meisenzahl EM (2003). Structural changes of the hippocampus and the amygdala in patients with major depression and healthy controls during a one year follow-up. Pharmacopsychiatry 36: ) Meisenzahl EM, Frodl T, Schmitt GJ, Zetzsche T, Dresel S, LaFougere G, Hahn K, Möller H-J (2003). Combined dopamine transporter and D2-receptor imaging in schizophrenia: Implications for atypical neuroleptics. Pharmacopsychiatry 36: ) Zetzsche T, Frodl T, Möller HJ, Meisenzahl EM (2004). Mögliche Zusammenhänge zwischen Amygdala- und Hippocampusvolumen und depressiver Symptomatik bei Patientinnen mit Borderline Persönlichkeitsstörung. Nervenarzt 75 (Suppl. 2): S220.

8 22) Frodl TS, Zetzsche T, Schmitt G (2005). Hippocampal and amygdala volume changes in patients with major depression and healthy controls during a three year follow-up. Pharmacopsychiatry 38 (5): ) Zetzsche T, Frodl TS, Schüle C, Baghai T, Seifert D, Tabrizi S, Preuss U, Schmitt G, Born C, Reiser M, Rupprecht R, Möller HJ, Meisenzahl EM (2005). Structural alterations of amygdala and hippocampus and HPA axis dysregulation in patients with borderline personality disorder. Pharmacopsychiatry 38 (5): ) Frodl TS, Zetzsche T, Schmitt G, Schlossbauer T, Jäger MW, Bottlender R, Reiser M, Möller HJ, Meisenzahl E (2005). Hippocampal and amygdala volume changes in patients with major depression and healthy controls during a three year follow-up. Pharmacopsychiatry 38 (5): ) Zetzsche T, Forsthoff A, Seemueller F (2005). Similar brain structural endophenotypes in borderline personality disorder (BPD) and bipolar affective disorder patients? A structural MRT study comparing amygdala volumes in both disorders. Bipolar Disorders 7 (Suppl. 2): ) Meisenzahl E, Schmitt G, Zetzsche T (2005). In vivo imaging of the dopaminergic neurotransmitter system in an animal model. European Psychiatry 20 (Suppl. 1): S70. 27) Koutsouleris N, Frodl T, Zetzsche T (2005). Voxel-based morphometry compared to regions-ofinterest techniques in a cross-sectional MRI study of schizophrenic patients and healthy controls. European Psychiatry 20 (Suppl. 1): S70-S71. 28) Meisenzahl E, Schmitt G, la Fougere C, Makowski M, Zetzsche T, Frodl T, Keck M, Müller M, Hahn K, Möller H-J, Dresel S (2005). In vivo imaging of the serotonergic neurotransmitter system in an animal model. European Psychiatry 20 (Suppl. 1): S ) Zetzsche T, Watz D, Frodl T (2005). Anterior cingulate gyrus in schizophrenic patients and controls: A structural magnetic resonance imaging evaluation. European Psychiatry 20 (Suppl. 1): S71. 30) Zetzsche T, Tabrizi SA, Seifert D (2005). Possible structural hippocampal alterations and HPA axis dysregulation in patients with borderline personality disorder. European Psychiatry 20 (Suppl. 1): S ) Meisenzahl EM, Koutsouleris N, Schlossbauer T, Schmitt G, Frodl T, Zetzsche T, Born C, Reiser M, Möller H-J (2005). Bedeutung des DTI zur Evaluation von Elektrokrampftherapie. Nervenarzt 76 (Suppl. 1): S ) Meisenzahl EM, Frodl T, Zetzsche T, Ufer S, Bottlender R, Jäger M, Sievers M, Decker P, Born C, Reiser M, Möller H-J (2005). Langzeitevaluation von schizophrenen und depressiven Patienten mit Kernspintomographie: Vergleich zwischen Erstmanifestation und Rezidiven. Nervenarzt 76 (Suppl. 1): S226.

9 33) Meisenzahl EM, Schmitt G, Koutsouleris N, Frodl T, Zetzsche T, Ufer S, Bottlender R, Jäger M, Sievers M, Decker P, Born C, Reiser M, Möller H-J (2005). Strukturelle MRT als Prädiktor für die Entstehung schizophrener Störungen. Nervenarzt 76 (Suppl. 1): S46. 34) Zetzsche T, Tabrizi S, Koutsouleris N, Möller H-J, Meisenzahl EM (2006). Hippocampal volume and aggressive behaviour in patients with borderline personality disorder. European Archives of Psychiatry and Clinical Neuroscience 256 (Suppl. 2): WS ) Beraldi A, Zetzsche T, Born C, Meindl T, Engel RR, Reiser M, Möller H-J, Fast K (2006). Emotion perception and modulation in patients with borderline personality disorder and its effect on memory performance. European Archives of Psychiatry and Clinical Neuroscience 256 (Suppl. 2): WS ) Beraldi A, Zetzsche T, Engel RR, Herpertz SC, Ruppel B, Möller H-J, Fast K (2006). Neuropsychological results in patients with borderline personality disorder. European Archives of Psychiatry and Clinical Neuroscience 256 (Suppl. 2): WS ) Erhardt A, Naumann P, Unschuld GP, Zetzsche T, Zwanzger P, Rupprecht R, Meisenzahl E, Keck ME (2006). Volumetric magnetic resonance imaging of limbic structures in panic disorder. European Archives of Psychiatry and Clinical Neuroscience 256 (Suppl. 2): S ) Zetzsche T, Frodl T, Schmitt G, Watz D, Born C, Reiser M, Möller H-J, Meisenzahl EM (2006). Anterior cingulate gyrus abnormalities in schizophrenic patients as detected by strutural MRI. Neuro- Image 31: S ) Frodl T, Zetzsche T, Höhne T, Banac S, Jäger M, Schlossbauer T, Leinsinger G, Schmitt, G, Bottlender R, Reiser M, Möller, H-J, Meisenzahl EM (2006). Three year follow-up prospective MRI of the hippocampus in patients with major depression and healthy controls. NeuroImage 31: S ) Meisenzahl EM, Ottes T, Zetzsche T, Frodl T, Koutsouleris N, Schmitt G, Born C, Reiser C, Möller H-J (2006). Neuroplasticity in brain structure of patients with schizophrenia: A 6-year follow-up MRI study. NeuroImage 31: S ) Schlossbauer T, Koutsouleris N, Reiser M, Born C, Zetzsche T, Frodl T, Scheuerecker J, Schmitt G, Möller H-J, Meisenzahl EM (2006). Evaluation of electroconvulsive therapy in drug-resistant major depression through diffusion tensor imaging. NeuroImage 31: S ) Schlossbauer T, Koutsouleris N, Born C, Reiser M, Zetzsche T, Frodl T, Scheuerecker J, Schmitt G, Möller H-J, Meisenzahl EM (2006). Disconnectivity of frontal and limbic cortices in major depression measured by diffusion tensor imaging. NeuroImage 31: S ) Frodl T, Albrecht J, Koutsouleris N, Scheuerecker J, Rzezika AM, Linn J, Brückmann H, Zetzsche T, Schmitt G, Möller H-J, Wiesmann M, Meisenzahl EM (2006). Explicit and implicit facial affect recognition in patients with major depression and healthy controls: A functional magnetic resonance imaging follow-up therapy study. NeuroImage 31: S122.

10 44) Beraldi A, Fast K, Meindl T, Zetzsche T, Born C, Reiser M, Engel R (2006). Neurofunctional results of emotion perception and emotion regulation in patients with borderline personality disorder (BPD). NeuroImage 31: S89. 45) Scheuerecker J, Ufer S, Wiesmann M, Zetzsche T, Frodl T, Koutsouleris N, Forsthoff A, Bruckmann K, Möller H-J, Meisenzahl EM (2006). Neuronal network disconnection in untreated first episode schizophrenic patients - a fmri study. NeuroImage 31: S59. 46) Scheuerecker J, Zipse M, Ufer S, Wiesmann M, Zetzsche T, Frodl T, Koutsouleris N, Forsthoff A, Bruckmann K, Möller H-J, Meisenzahl EM (2006). Neuronal network disconnection in schizophrenia: effects of neuroleptic treatment with quetiapine - a fmri study. NeuroImage 31: S40. 47) Zetzsche T, Preuss UW, Frodl TS, Watz D, Schmitt G, Koutsouleris N, Born C, Reiser M, Möller H- J, Meisenzahl EM (2007). In-vivo topography of structural alterations of the anterior cingulate gyrus in schizophrenia. Pharmacopsychiatry 40: ) Frodl T, Jäger M, Born C, Ritter S, Kraft E, Zetzsche T, Bottlender R, Leinsinger G, Reiser M, Möller HJ, Meisenzahl E (2007). Die Bedeutung des anterioren cingulären Cortex im funktionellen Netzwerk der Affektregulation depressiver Patienten. Nervenarzt 78 (Suppl. 2): S255. Vorträge (publiziert): 1) Zetzsche T, Preuss U, Frodl T, Möller H-J, Meisenzahl EM (2001). Evidence for a correlation between thalamic structures and psychopharmacology in schizophrenia? An in-vivo MRI study with 50 schizophrenic patients. Pharmacopsychiatry 34: 210. (Vortrag, Kongress der Arbeitsgemeinschaft für Neuropsychopharmakologie und Pharmakopsychiatrie (AGNP), Nürnberg). 2) Zetzsche T, Preuss U, Frodl T, Münchhausen E, Möller H-J, Meisenzahl EM (2002). Borderline personality disorder and morphological brain changes: A structural magnetic resonance imaging study. European Archives of Psychiatry and Clinical Neuroscience 252: 64. (Vortrag, Internationaler Kongress über Theorie und Therapie von Persönlichkeitsstörungen (IKTTP) und European Congress on Personality Disorders (ISSPD), München). 3) Zetzsche T, Preuss U, Möller H-J, Meisenzahl EM (2002). Borderline-Persönlichkeitsstörung, aggressives und impulsives Verhalten und morphologische Gehirnveränderungen: Eine strukturelle kernspintomographische Untersuchung. Nervenarzt 73, Suppl. 1: 96. (Vortrag, Kongress der Deutschen Gesellschaft für Psychiatrie, Psychotherapie und Nervenheilkunde (DGPPN), Berlin). 4) Zetzsche T, Meisenzahl EM (2003). Brain data bases beyond nosology: Specificity of brain alterations and concepts of psychiatric disorders. World Psychiatry 2 (Suppl. 1): S14.

11 (Vortrag, Congress of the World Psychiatric Association (WPA) - International Thematic Conference: Diagnosis in Psychiatry: Integrating the Sciences, Wien). 5) Zetzsche T, Preuss U, Frodl T, Bondy B, Möller H-J, Meisenzahl M (2003). Mögliche genetische Einflussfaktoren auf die Gehirnstruktur von Patientinnen mit Borderline Persönlichkeitsstörung. Nervenarzt 74 (Suppl. 2): S94. (Vortrag, Kongress der Deutschen Gesellschaft für Psychiatrie, Psychotherapie und Nervenheilkunde (DGPPN), Berlin). 6) Zetzsche T (2005). Possible genetic influences on structural brain changes in patients with borderline personality disorder. The World Journal of Biological Psychiatry 6 (Suppl. 1): S143. (Vortrag, 8th World Congress of the World Federation of Societies of Biological Psychiatry, Wien). 7) Zetzsche T (2005). Neurobiology of patients with borderline personality disorder: CNS imaging, neuropsychological and clinical symptoms. European Psychiatry 20 (Suppl. 1): S187-S188 (Vortrag, Congress of the Association of European Psychiatrists (AEP), München). 8) Zetzsche T, Preuss U, Schmitt G, Seifert D, Münchhausen E, Tabrizi S, Leinsinger G, Born C, Reiser M, Möller H-J, Meisenzahl EM (2005). Strukturelle Veränderungen im Bereich des limbischen Systems und aggressives Verhalten bei Patientinnen mit Borderline Persönlichkeitsstörung. Nervenarzt 76 (Suppl. 1): S245. (Vortrag, Kongress der Deutschen Gesellschaft für Psychiatrie, Psychotherapie und Nervenheilkunde (DGPPN), Berlin). 9) Zetzsche T, Seifert D, Schmitt G, Möller H-J, Meisenzahl EM (2006). Structural changes of the temporolimbic system in patients with affective disorder and with personality disorder: Potential influences of polymorphism of the 5-HT system. European Archives of Psychiatry and Clinical Neuroscience 256 (Suppl. 2): S (Vortrag, 9th Congress of the German Society for Biological Psychiatry, Munich, Germany). 10) Zetzsche T, Preuss UW, Bondy B, Frodl T, Rujescu D, Möller H-J, Meisenzahl EM (2006). Genetic variants of the serotonin system and limbic structures in psychiatric disorders. European Psychiatry 21 (Suppl. 1): S 12. (Vortrag, Congress of the Association of European Psychiatrists (AEP), Nizza). 11) Zetzsche T, Preuss UW, Bondy B, Frodl T, Rujescu D, Möller H-J, Meisenzahl EM Zetzsche T, Bobes J, De la Fuente JM, Pogarell O, Norra C (2007). Do brain imaging and neurophysiology differentiate borderline disorder and depression? European Psychiatry 22, S35. (Vortrag, Congress of the Association of European Psychiatrists (AEP), Madrid). 12) Zetzsche T, Preuss U, Frodl T, Watz D, Schmitt G, Koutsouleris N, Born C, Reiser M, Möller H-J, Meisenzahl EM (2007). In-vivo Topographie struktureller Veränderungen des anterioren Gyrus cinguli bei schizophrenen Störungen. Nervenarzt 78 (Suppl. 2): S255. (Vortrag, Kongress der Deutschen Gesellschaft für Psychiatrie, Psychotherapie und Nervenheilkunde (DGPPN), Berlin).

12 Weitere Vorträge (nicht publiziert, Auswahl): 1) Zetzsche T, Meisenzahl EM, Frodl T, Schmitt G, Preuss UW, Leinsinger G, Möller HJ: Zusammenhänge zwischen Amygdala Volumen und depressiver Symptomatik bei Patientinnen mit Borderline Persönlichkeitsstörung Seminar für Biologische Psychiatrie, 2005, Oberlech, Österreich 2) Zetzsche T, Frodl T, Schmitt G, Koutsouleris N, Rujescu D, Rüther T, Ufer S, Born C, Reiser M, Bondy B, Meisenzahl EM, Möller H-J: Ergebnisse struktureller MRT Untersuchungen in der Schizophrenieforschung und deren Bedeutung für Pathogenese und Krankheitsverlauf Research Festival, Klinik für Psychiatrie und Psychotherapie, Ludwig-Maximilians-Universität, 2005, München 3) Zetzsche T: Persönlichkeitsstörungen: Pathogenese, Diagnostik und Therapie Neuroscience Excellence Program, Klinik für Psychiatrie und Psychotherapie, Ludwig-Maximilians-Universität, 2005, München 4) Zetzsche T, Meisenzahl EM: Bildgebende Verfahren bei Depression, Schizophrenie und Persönlichkeitsstörungen: Gemeinsame und unterschiedliche Befunde Klinik für Psychiatrie und Psychotherapie, Universität Rostock, 2005, Rostock 5) Zetzsche T, Preuss U, Frodl T, Tabrizi S, Möller H-J, Meisenzahl EM: Neurobiologische Veränderungen bei der Borderline Persönlichkeitsstörung 10. Kongress der Deutschen Gesellschaft für Verhaltensmedizin und Verhaltensmodifikation (DGVM), März 2007, München 6) Zetzsche T, Preuss UW, Frodl T, Schmitt G, Seifert D, Koutsouleris N, Fast K, Möller H-J, Meisenzahl EM: Neurobiologie der Borderline Persönlichkeitsstörung 10. Psychiatriepflegetag April 2007, München 7) Zetzsche T, Preuss UW, Frodl T, Bondy B, Seifert D, Zill P, Rujescu D, Reiser M, Möller H-J, Meisenzahl EM: Neurobiologie der Borderline Persönlichkeitsstörung Fortbildung für Neurologen, Psychiater und Psychotherapeuten am Zentrum für psychische Gesundheit, Klinikum Ingolstadt, 12. September 2007, Ingolstadt 8) Zetzsche T, Preuss UW, Frodl T, Schmitt G, Seifert D, Koutsouleris N, Fast K, Möller H-J, Meisenzahl EM: Neurobiology of Borderline Personality Disorder Universitätsspital Zürich, 19. September 2007, Schweiz 9) Zetzsche T, Preuss UW, Frodl T, Bondy B, Seifert D, Zill P, Rujescu D, Reiser M, Meisenzahl EM, Möller H-J: Neurobiologische Grundlagen für die Therapie der Borderline-Störung 23. Münchner Forum Psychiatrie für die Praxis, 1. Dezember 2007, München

13 10) Zetzsche T: Hirnstrukturelle Veränderungen temporolimbischer Regionen bei der Borderline Persönlichkeitsstörung 26. Symposium der Arbeitsgemeinschaft für Neuropsychopharmakologie und Pharmakopsychiatrie (AGNP),8. Oktober 2009, München 11) Zetzsche T: Structural changes of the temporolimbic system and associations between amygdala volume, depression and a functional serotonin 1A receptor gene polymorphism in borderline personality disorder 1. International Congress on Borderline Personality Disorder, 2. Juli 2010, Berlin 12) Zetzsche T, Meisenzahl EM, Koutsouleris N, Frodl T: Das temporolimbische System bei der Borderline Persönlichkeitsstörung: Mögliche Einflüsse durch Stress und Genetik 7. Internationaler Kongress über Theorie und Therapie von Persönlichkeitsstörungen, 10. Juli 2010, München 13) Zetzsche T: Vergleichende Analyse regionaler Gehirnveränderungen (ROI und VBM) bei der Persönlichkeitsstörung vom Borderline Typus" Research Festival, Klinik für Psychiatrie und Psychotherapie, Ludwig-Maximilians-Universität, 29. Juli 2011, München Organisation/Vorsitz von Symposien: 1. Treatment of schizophrenia 22. Kongress der Arbeitsgemeinschaft Neuropsychopharmakologie und Pharmakopsychiatrie (AGNP), September 2001, Nurnberg, Germany. 2. Neurobiology and Pharmacotherapy of Personality Disorders 5th International Society for the Study of Personality Disorders (ISSPD) European Congress on Personality Disorders; with/mit 3. Internationaler Kongress über Theorie und Therapie von Persönlichkeitsstörungen July 2002, Munich, Germany. 3. Neurobiological, genetic and developmental aspects of personality disorders 13th European Congress of Psychiatry, Association of European Psychiatrists (AEP), April 2005, Munich, Germany. 4. Neurobiological changes in patients with borderline personality disorder 8th World Congress of Biological Psychiatry, World Federation of Societies of Biological Psychiatry (WFSBP), 28. June 3. July 2005, Vienna, Austria. 5. Suizidalität, Impulsivität, Aggressivität: Neurobiologische und genetische Befunde Kongress der Deutschen Gesellschaft für Psychiatrie, Psychotherapie und Nervenheilkunde (DGPPN), November 2005, Berlin. 6. Serotonin and neuroplasticity: Impact of genetics and environment

14 14th European Congress of Psychiatry, Association of European Psychiatrists (AEP), March 2006, Nice, France. 7. The amygdala: Neurobiology, genetics, and alterations in psychiatric disorders 9th Congress of the German Society for Biological Psychiatry, October 2006, Munich, Germany. 8. Do brain imaging and neurophysiology differentiate borderline disorder and depression? 15th European Congress of Psychiatry, Association of European Psychiatrists (AEP), March 2007, Madrid, Spain. 9. Die Rolle des anterioren Cingulums bei psychischen Störungen Kongress der Deutschen Gesellschaft für Psychiatrie, Psychotherapie und Nervenheilkunde (DGPPN), November 2007, Berlin. 10. Prävention von Gewaltdelikten bei Kindern und Jugendlichen und Umgang mit Aggressivität bei Persönlichkeitsstörungen 7. Internationaler Kongress über Theorie und Therapie von Persönlichkeitsstörungen, Juli 2010, München