Grants Forschungsförderung

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1 Grants Forschungsförderung We appreciate the continuous support for our research projects by the following grant providers (for details see next pages): Wir bedanken uns bei folgenden Forschungsförderern für die Unterstützung unserer Forschungsprojekte (siehe Details auf den nächsten Seiten): Ongoing Projects Previous Projects 1

2 Ongoing Projects Rupp Structure-function investigations of human afamin FWF Coassin Application of Third Generation Sequencing to the genotyping of the Lipoprotein(a) KIV-2 repeat MUI-Start Coassin Development of an ultra-deep sequencing approach for the analysis of the lipoprotein(a) KIV-2 repeat D-A-C-H Gesellschaft Prävention von Herz- Kreislauf-Erkrankunge e.v Fendt Mitochondrial DNA methylation as epigenetic risk marker for the development of prostate cancer Krebshilfe Tirol Lamina A genome-wide approach to evaluate the genetic basis of lipoprotein(a) SAXCESS Structure-function analysis of the human plasma glycoprotein afamin, a potential drug target in the treatment of metabolic syndrome. FWF EU (Marie Curie) Forer / Schönherr / Weißensteiner / Scalable Big Data Bioinformatics Analysis in the Cloud OEAD HR12/ Fuchsberger Analysis of rare variants from sequencing data FWF Schrödinger- Rückkehrer 2014 ncrnapain: Non-coding RNAs in neurogenic and neuropathic pain mechanisms and their application for risk assessment, patient stratification and personalised pain medicine EU-FP7 No Tirol Score Land Tirol Kloss-Brandstätter Oralkarzinom Land Tirol Kloss-Brandstätter Mitochondrial markers for prostate cancer prognosis and therapy Oncotyrol Kloss-Brandstätter Mitochondrial DNA mutations in oral cancer Tiroler Wissenschaftsfonds German Chronic Kidney Disease Study Deut. BMBF und

3 Lamina GCKD Genetische Determination von HDL und Genotypisierung LOX Pathway und Kandidaten SNPs von SAPALDIA Relevanz A genome-wide approach to evaluate the genetic basis of lipoprotein(a) KFH- SAPALDIA FWF P [top] Previous Projects Epidemiologische Charakterisierung von Afamin FWF Afamin neue Diagnose und mögliche Therapie für neuro-degenerative Erkrankungen B2: Antisense Wirkstoffe zur Therapie von Hyperlipämie Forschungsförderungsgesellschaft (FFG) Afamin a possible novel biomarker for male infertility disorders Dr. Legerlotz 2006 Kloss-Brandstätter Mitochondrial DNA mutations in oral cancer Krebshilfe Tirol Kloss-Brandstätter Genetische Einflüsse auf den Cholesterinstoffwechsel ein neuer Zugang Kloss-Brandstätter Copy numer variations and genetic traits: insights into the origin of cardiovascular disease MFI Kloss-Brandstätter Mitochondrial DNA Mutations in Prostate Cancer Dr. Legerlotz Kollerits Identifizierung von Genen der peripheren arteriellen Verschlusskrankheit

4 Kollerits Assoziationsstudie zu metabolischen Parametern Tiroler Wissenschaftsfonds Kollerits A sequencing and genotyping approach to shed light on the genetic variation within ARFRP1 Dr. Legerlotz GOLD III - Genomics of Lipid-associated Disorders III GEN-AU A genome-wide association study to identify susceptibility genes for peripheral arterial disease and cardiovascular disease r Herzfonds Previous projects - to be continued 4

5 Previous projects - continued Apolipoprotein A-IV as metabolic and cardiovascular risk factor (Translational Research Project) Tiroler Zukunftsstiftung Genetische Analyse der Intima-Media-Dicke (IMD) der A. carotis (Klockgether, Ziegler, ) DFG, Germany Genetische Einflüsse auf Hämatokrit und Erythrozyten Tiroler Wissenschaftsfonds Genotyping and Sequencing Unit IFTZ Investigation of ATGL mutations and its association with free fatty acid and glucose metabolism Oncotyrol Core Facility Oncotyrol Genomweite Assoziationsstudie zu Adiponectin Tiroler Wissenschaftsfonds GOLD II - Genomics of Lipid-associated Disorders II GEN-AU UGT1A1 Polymorphism and coronary heart disease in the Framingham Heart Study Tiroler Wissenschaftsfonds "Methods of genetic epidemiology to analyze haplotype risk structures", Proj.-B10 of SFB 386: "Statistical Analysis of Discrete Structures" (Heid,, Illig and Wichmann) SFB der Deutsche Forschungsgemeinschaft Genetic influence on HDL cholesterol and triglyceride concentrations in hemodialysis patients and its association with atherosclerotic complications Genzyme Renal Innovations Program, USA GOLD I - Genomics of Lipid-associated Disorders I GEN-AU Prospective investigation of the cardiovascular and cerebrovascular risk in patients with intermittent claudication und Österr. Herzfonds Danubian Biobank-SSA EU ESCAPE-Study EU (subcontract) Previous projects - to be continued 5

6 Previous projects - continued Susceptibility gene(s) for type-i diabetes mellitus on chromosome 6q27 Diabetes Gesellschaft Apolipoprotein A-IV and its role in coronary artery disease FWF Apolipoprotein A-IV in patients with renal disease r Herzfonds, Else Kröner-Fresenius-, Dr. Legerlotz Segregation, linkage and association studies of small dense LDL particles Akademie der Wissenschaften (APART- Stipendium) Lp(a), apo(a) phenotype and apoa-iv and the progression of atherosclerosis in the carotid arteries r Herzfonds Untersuchungen zum gestörten Stoffwechsel von Lipoprotein(a) bei Niereninsuffizienz Lingenhel Search for mutations in carriers of the minor allele of ATGL SNP5 and SNP9 and its association with free fatty acid and glucose Dr. Legerlotz [top] 6